Gene: SLC8A3

Alternate names for this Gene: NCX3

Gene Summary: This gene encodes a member of the sodium/calcium exchanger integral membrane protein family. Na+/Ca2+ exchange proteins are involved in maintaining Ca2+ homeostasis in a wide variety of cell types. The protein is regulated by intracellular calcium ions and is found in both the plasma membrane and intracellular organellar membranes, where exchange of Na+ for Ca2+ occurs in an electrogenic manner. Alternative splicing has been observed for this gene and multiple variants have been described.

Gene is located in Chromosome: 14

Location in Chromosome : 14q24.2

Description of this Gene: solute carrier family 8 member A3

Type of Gene: protein-coding

rs41286548 in SLC8A3 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.