Gene: SLCO1A2

Alternate names for this Gene: OATP|OATP-A|OATP1A2|SLC21A3

Gene Summary: This gene encodes a sodium-independent transporter which mediates cellular uptake of organic ions in the liver. Its substrates include bile acids, bromosulphophthalein, and some steroidal compounds. The protein is a member of the SLC21A family of solute carriers. Alternative splicing of this gene results in multiple transcript variants.

Gene is located in Chromosome: 12

Location in Chromosome : 12p12.1

Description of this Gene: solute carrier organic anion transporter family member 1A2

Type of Gene: protein-coding

Gene: IAPP

Alternate names for this Gene: DAP|IAP

Gene Summary: This gene encodes a member of the calcitonin family of peptide hormones. This hormone is released from pancreatic beta cells following food intake to regulate blood glucose levels and act as a satiation signal. Human patients with type 1 and advanced type 2 diabetes exhibit reduced levels of the encoded hormone in blood and pancreas. This protein also exhibits a bactericidal, antimicrobial activity.

Gene is located in Chromosome: 12

Location in Chromosome : 12p12.1

Description of this Gene: islet amyloid polypeptide

Type of Gene: protein-coding

rs144436375 in SLCO1A2;IAPP gene and Blood Protein Measurement PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.