Gene: SORCS2

Alternate names for this Gene: -

Gene Summary: This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.1

Description of this Gene: sortilin related VPS10 domain containing receptor 2

Type of Gene: protein-coding

Gene: PSAPL1

Alternate names for this Gene: -

Gene Summary: This gene encodes a protein that is related to the glycoprotein prosaposin. Based on sequence similarity between the encoded protein and prosaposin, it is predicted that the encoded protein is a preproprotein that is proteolytically processed to generate multiple protein products. These predicted products include saposins A-like, B-like, C-like, and D-like, which may play a role in the lysosomal degradation of sphingolipids.

Gene is located in Chromosome: 4

Location in Chromosome : 4p16.1

Description of this Gene: prosaposin like 1

Type of Gene: protein-coding

rs10023470 in SORCS2;PSAPL1 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.