Gene: SPARC

Alternate names for this Gene: BM-40|OI17|ON|ONT

Gene Summary: This gene encodes a cysteine-rich acidic matrix-associated protein. The encoded protein is required for the collagen in bone to become calcified but is also involved in extracellular matrix synthesis and promotion of changes to cell shape. The gene product has been associated with tumor suppression but has also been correlated with metastasis based on changes to cell shape which can promote tumor cell invasion. Three transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 5

Location in Chromosome : 5q33.1

Description of this Gene: secreted protein acidic and cysteine rich

Type of Gene: protein-coding