Gene: TP53INP1

Alternate names for this Gene: SIP|TP53DINP1|TP53INP1A|TP53INP1B|Teap|p53DINP1

Gene Summary:

Gene is located in Chromosome: 8

Location in Chromosome : 8q22.1

Description of this Gene: tumor protein p53 inducible nuclear protein 1

Type of Gene: protein-coding

Gene: NDUFAF6

Alternate names for this Gene: C8orf38|FRTS5|MC1DN17

Gene Summary: This gene encodes a protein that localizes to mitochondria and contains a predicted phytoene synthase domain. The encoded protein plays an important role in the assembly of complex I (NADH-ubiquinone oxidoreductase) of the mitochondrial respiratory chain through regulation of subunit ND1 biogenesis. Mutations in this gene are associated with complex I enzymatic deficiency.

Gene is located in Chromosome: 8

Location in Chromosome : 8q22.1

Description of this Gene: NADH:ubiquinone oxidoreductase complex assembly factor 6

Type of Gene: protein-coding

rs1320164 in TP53INP1;NDUFAF6 gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

PMID 20581827 2010 Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis.

PMID 21647700 2011 Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.

PMID 23300278 2013 Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India.

rs896854 in TP53INP1;NDUFAF6 gene and Eosinophil count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.