Gene: TSEN34

Alternate names for this Gene: LENG5|PCH2C|SEN34|SEN34L

Gene Summary: This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.42

Description of this Gene: tRNA splicing endonuclease subunit 34

Type of Gene: protein-coding