Gene: TXNL4B

Alternate names for this Gene: DLP|Dim2

Gene Summary:

Gene is located in Chromosome: 16

Location in Chromosome : 16q22.2

Description of this Gene: thioredoxin like 4B

Type of Gene: protein-coding

Gene: HPR

Alternate names for this Gene: A-259H10.2|HP

Gene Summary: This gene encodes a haptoglobin-related protein that binds hemoglobin as efficiently as haptoglobin. Unlike haptoglobin, plasma concentration of this protein is unaffected in patients with sickle cell anemia and extensive intravascular hemolysis, suggesting a difference in binding between haptoglobin-hemoglobin and haptoglobin-related protein-hemoglobin complexes to CD163, the hemoglobin scavenger receptor. This protein may also be a clinically important predictor of recurrence of breast cancer.

Gene is located in Chromosome: 16

Location in Chromosome : 16q22.2

Description of this Gene: haptoglobin-related protein

Type of Gene: protein-coding

rs217184 in TXNL4B;HPR gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs34042070 in TXNL4B;HPR gene and Cardiovascular Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs34042070 in TXNL4B;HPR gene and Low density lipoprotein cholesterol measurement PMID 30670697 2019 Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity.

rs34042070 in TXNL4B;HPR gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

rs217184 in TXNL4B;HPR gene and Serum total cholesterol measurement PMID 30718733 2019 The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.