Gene: UBD

Alternate names for this Gene: FAT10|GABBR1|UBD-3

Gene Summary: This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: ubiquitin D

Type of Gene: protein-coding

Gene: GABBR1

Alternate names for this Gene: GABABR1|GABBR1-3|GB1|GPRC3A

Gene Summary: This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.

Gene is located in Chromosome: 6

Location in Chromosome : 6p22.1

Description of this Gene: gamma-aminobutyric acid type B receptor subunit 1

Type of Gene: protein-coding