Gene: UBE2G1

Alternate names for this Gene: E217K|UBC7|UBE2G

Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins. The protein may be involved in degradation of muscle-specific proteins.

Gene is located in Chromosome: 17

Location in Chromosome : 17p13.2

Description of this Gene: ubiquitin conjugating enzyme E2 G1

Type of Gene: protein-coding

rs9893691 in UBE2G1 gene and Waist-Hip Ratio PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.