Gene: UBE2Z

Alternate names for this Gene: HOYS7|USE1

Gene Summary: This gene encodes an enzyme which ubiquitinates proteins which participate in signaling pathways and apoptosis.

Gene is located in Chromosome: 17

Location in Chromosome : 17q21.32

Description of this Gene: ubiquitin conjugating enzyme E2 Z

Type of Gene: protein-coding

rs1057902 in UBE2Z gene and Body Height PMID 31562340 2019 Characterizing rare and low-frequency height-associated variants in the Japanese population.

rs145067756 in UBE2Z gene and Cerebrovascular accident PMID 21957438 2011 Genomic risk profiling of ischemic stroke: results of an international genome-wide association meta-analysis.

rs46522 in UBE2Z gene and Coronary heart disease PMID 21378990 2011 Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.

rs1058018 in UBE2Z gene and Diabetes Mellitus, Non-Insulin-Dependent PMID 27362418 2016 A Powerful Procedure for Pathway-Based Meta-analysis Using Summary Statistics Identifies 43 Pathways Associated with Type II Diabetes in European Populations.

PMID 29358691 2018 Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes.

PMID 30054458 2018 Genome-wide association analyses identify 143 risk variants and putative regulatory mechanisms for type 2 diabetes.