Gene: UHRF1BP1

Alternate names for this Gene: C6orf107|ICBP90|dJ349A12.1

Gene Summary:

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.31

Description of this Gene: UHRF1 binding protein 1

Type of Gene: protein-coding

Gene: TAF11

Alternate names for this Gene: MGC:15243|PRO2134|TAF2I|TAFII28

Gene Summary: Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. This subunit also interacts with another small subunit, TAF13, to form a heterodimer with a structure similar to the histone core structure. Two transcript variants encoding different isoforms have been found for this gene.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.31

Description of this Gene: TATA-box binding protein associated factor 11

Type of Gene: protein-coding

rs4646947 in UHRF1BP1;TAF11 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.