Gene: UST

Alternate names for this Gene: 2OST

Gene Summary: Uronyl 2-sulfotransferase transfers sulfate to the 2-position of uronyl residues, such as iduronyl residues in dermatan sulfate and glucuronyl residues in chondroitin sulfate (Kobayashi et al., 1999 [PubMed 10187838]).[supplied by OMIM, Mar 2008]. ##Evidence-Data-START## Transcript exon combination :: AB020316.1, SRR1803615.39716.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000367463.5/ ENSP00000356433.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END##

Gene is located in Chromosome: 6

Location in Chromosome : 6q25.1

Description of this Gene: uronyl 2-sulfotransferase

Type of Gene: protein-coding

rs17669546 in UST gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs13211840 in UST gene and Diastolic blood pressure PMID 27271309 2016 The 1 df tests identified interactions for UST rs13211840 on diastolic BP (P=3.13×10(-9)).

rs34969510 in UST gene and Serum albumin measurement PMID 22286219 2012 Genome-wide association study identifies multiple loci influencing human serum metabolite levels.

rs13211840 in UST gene and Sodium measurement PMID 27271309 2016 Genome-Wide Gene-Sodium Interaction Analyses on Blood Pressure: The Genetic Epidemiology Network of Salt-Sensitivity Study.