Gene: VANGL2

Alternate names for this Gene: LPP1|LTAP|STB1|STBM|STBM1

Gene Summary: The protein encoded by this gene is a membrane protein involved in the regulation of planar cell polarity, especially in the stereociliary bundles of the cochlea. The encoded protein transmits directional signals to individual cells or groups of cells in epithelial sheets. This protein is also involved in the development of the neural plate.

Gene is located in Chromosome: 1

Location in Chromosome : 1q23.2

Description of this Gene: VANGL planar cell polarity protein 2

Type of Gene: protein-coding

rs12083518 in VANGL2 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs267607167 in VANGL2 gene and NEURAL TUBE DEFECTS, SUSCEPTIBILITY TO PMID 20558380 2010 VANGL2 mutations in human cranial neural-tube defects.