Gene: ZBTB20

Alternate names for this Gene: DPZF|HOF|ODA-8S|PRIMS|ZNF288

Gene Summary: This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Gene is located in Chromosome: 3

Location in Chromosome : 3q13.31

Description of this Gene: zinc finger and BTB domain containing 20

Type of Gene: protein-coding

Gene: ZBTB20-AS5

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