Gene: ZFPM2-AS1

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

Type of Gene:

Gene: ZFPM2

Alternate names for this Gene: DIH3|FOG2|SRXY9|ZC2HC11B|ZNF89B|hFOG-2

Gene Summary: The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence.

Gene is located in Chromosome: 8

Location in Chromosome : 8q23.1

Description of this Gene: zinc finger protein, FOG family member 2

Type of Gene: protein-coding

rs4734879 in ZFPM2-AS1;ZFPM2 gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

rs3832566 in ZFPM2-AS1;ZFPM2 gene and Blood basophil count (lab test) PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs16873402 in ZFPM2-AS1;ZFPM2 gene and Vascular Endothelial Growth Factor Measurement PMID 21757650 2011 Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels.

rs4734879 in ZFPM2-AS1;ZFPM2 gene and Venous Thromboembolism PMID 31676865 2019 Genome-wide association analysis of venous thromboembolism identifies new risk loci and genetic overlap with arterial vascular disease.

rs7832219 in ZFPM2-AS1;ZFPM2 gene and White Blood Cell Count procedure PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.