Gene: ZFYVE9

Alternate names for this Gene: MADHIP|NSP|PPP1R173|SARA|SMADIP

Gene Summary: This gene encodes a double zinc finger motif-containing protein that participates in the transforming growth factor-beta (TGFB) signalling pathway. The encoded protein interacts directly with SMAD2 and SMAD3, and recruits SMAD2 to the TGFB receptor. There are multiple pseudogenes for this gene on chromosomes 2, 15, and X. Alternative splicing results in multiple transcript variants.

Gene is located in Chromosome: 1

Location in Chromosome : 1p32.3

Description of this Gene: zinc finger FYVE-type containing 9

Type of Gene: protein-coding

rs17401875 in ZFYVE9 gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs114151376 in ZFYVE9 gene and Intelligence PMID 29844566 2018 Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function.