Gene: ZNF420

Alternate names for this Gene: APAK

Gene Summary: The protein encoded by this gene is a KRAB-type zinc finger protein that negatively-regulates p53-mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.

Gene is located in Chromosome: 19

Location in Chromosome : 19q13.12

Description of this Gene: zinc finger protein 420

Type of Gene: protein-coding