Variant: rs422951 

    present in Gene: NOTCH4
    present in Chromosome: 6
    Position on Chromosome: 32220606
    Alleles of this Variant: T/C

rs422951 in NOTCH4 gene and Age related macular degeneration PMID 22694956 2012 Genome-wide association study of age-related macular degeneration identifies associated variants in the TNXB-FKBPL-NOTCH4 region of chromosome 6p21.3.

rs422951 in NOTCH4 gene and Hepatitis B, Chronic PMID 25802187 2015 Genetic variants in five novel loci including CFB and CD40 predispose to chronic hepatitis B.

rs422951 in NOTCH4 gene and Rheumatoid Arthritis PMID 19503088 2009 REL, encoding a member of the NF-kappaB family of transcription factors, is a newly defined risk locus for rheumatoid arthritis.