Condition: Malignant Head and Neck Neoplasm


rs4804217 in PCP2 gene and Malignant Head and Neck Neoplasm PMID 29884837 2018 We identified four common SNPs representing four genomic regions: 7q22.3 (rs10950641; SNX8; P = 3.39 × 10<sup>-14</sup>), 19p13.2 (rs4804217; PCP2; P = 2.95 × 10<sup>-9</sup>), 3q27.3 (rs6796803; KNG1; P = 6.42 × 10<sup>-9</sup>) and 15q22.2 (rs4775319; RORA; P = 1.02 × 10<sup>-8</sup>), suggesting SNX8, PCP2, KNG1 and RORA might be novel target genes for NP in patients with head and neck cancer.

rs4775319 in RORA gene and Malignant Head and Neck Neoplasm PMID 29884837 2018 We identified four common SNPs representing four genomic regions: 7q22.3 (rs10950641; SNX8; P = 3.39 × 10<sup>-14</sup>), 19p13.2 (rs4804217; PCP2; P = 2.95 × 10<sup>-9</sup>), 3q27.3 (rs6796803; KNG1; P = 6.42 × 10<sup>-9</sup>) and 15q22.2 (rs4775319; RORA; P = 1.02 × 10<sup>-8</sup>), suggesting SNX8, PCP2, KNG1 and RORA might be novel target genes for NP in patients with head and neck cancer.

rs10950641 in SNX8 gene and Malignant Head and Neck Neoplasm PMID 29884837 2018 We identified four common SNPs representing four genomic regions: 7q22.3 (rs10950641; SNX8; P = 3.39 × 10<sup>-14</sup>), 19p13.2 (rs4804217; PCP2; P = 2.95 × 10<sup>-9</sup>), 3q27.3 (rs6796803; KNG1; P = 6.42 × 10<sup>-9</sup>) and 15q22.2 (rs4775319; RORA; P = 1.02 × 10<sup>-8</sup>), suggesting SNX8, PCP2, KNG1 and RORA might be novel target genes for NP in patients with head and neck cancer.