rs7913447 in ANAPC16 gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs1800057 in ATM gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs869025212 in BAP1 gene and Renal Cell Carcinoma

PMID 25687217 2015 Analysis of BAP1 Germline Gene Mutation in Young Uveal Melanoma Patients.

rs4903064 in DPF3 gene and Renal Cell Carcinoma

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10^-10), 3p22.1 (rs67311347, P=2.5 × 10^-8), 3q26.2 (rs10936602, P=8.8 × 10^-9), 8p21.3 (rs2241261, P=5.8 × 10^-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10^-8), 11q22.3 (rs74911261, P=2.1 × 10^-10) and 14q24.2 (rs4903064, P=2.2 × 10^-24).

rs1057519973 in ELOC gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs10211665 in EPAS1 gene and Renal Cell Carcinoma

PMID 21131975 2011 Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

PMID 22010048 2012 A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.

PMID 21131975 2011 Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC.

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

PMID 25826619 2015 Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer.

PMID 21131975 2011 Two correlated variants (r² = 0.99 in controls), rs11894252 (P = 1.8 × 10⁻⁸) and rs7579899 (P = 2.3 × 10⁻⁹), map to EPAS1 on 2p21, which encodes hypoxia-inducible-factor-2 alpha, a transcription factor previously implicated in RCC.

rs4381241 in FAF1 gene and Renal Cell Carcinoma

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10^-10), 3p22.1 (rs67311347, P=2.5 × 10^-8), 3q26.2 (rs10936602, P=8.8 × 10^-9), 8p21.3 (rs2241261, P=5.8 × 10^-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10^-8), 11q22.3 (rs74911261, P=2.1 × 10^-10) and 14q24.2 (rs4903064, P=2.2 × 10^-24).

rs7697932 in H2AZ1-DT gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs4804368 in INSR gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs1049380 in ITPR2 gene and Renal Cell Carcinoma

PMID 22010048 2012 We identified two common variants in linkage disequilibrium, rs718314 and rs1049380 (r(2) = 0.64, D ' = 0.84), in the inositol 1,4,5-triphosphate receptor, type 2 (ITPR2) gene on 12p11.23 as novel susceptibility loci for RCC (P = 8.89 × 10(-10) and P = 6.07 × 10(-9), respectively, in meta-analysis) with an allelic odds ratio of 1.19 [95% confidence interval (CI): 1.13-1.26] for rs718314 and 1.18 (95% CI: 1.12-1.25) for rs1049380.

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs234043 in LINC02068 gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs7105934 in LOC102724265 gene and Renal Cell Carcinoma

PMID 21131975 2011 Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

PMID 22010048 2012 A genome-wide association study identifies a novel susceptibility locus for renal cell carcinoma on 12p11.23.

rs718314 in LOC105369705 gene and Renal Cell Carcinoma

PMID 22010048 2012 We identified two common variants in linkage disequilibrium, rs718314 and rs1049380 (r(2) = 0.64, D ' = 0.84), in the inositol 1,4,5-triphosphate receptor, type 2 (ITPR2) gene on 12p11.23 as novel susceptibility loci for RCC (P = 8.89 × 10(-10) and P = 6.07 × 10(-9), respectively, in meta-analysis) with an allelic odds ratio of 1.19 [95% confidence interval (CI): 1.13-1.26] for rs718314 and 1.18 (95% CI: 1.12-1.25) for rs1049380.

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

rs10936602 in LRRIQ4 gene and Renal Cell Carcinoma

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10^-10), 3p22.1 (rs67311347, P=2.5 × 10^-8), 3q26.2 (rs10936602, P=8.8 × 10^-9), 8p21.3 (rs2241261, P=5.8 × 10^-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10^-8), 11q22.3 (rs74911261, P=2.1 × 10^-10) and 14q24.2 (rs4903064, P=2.2 × 10^-24).

rs11637556 in MAP2K1 gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs121913668 in MET gene and Renal Cell Carcinoma

PMID 9140397 1997 Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas.

rs1057519913 in MTOR gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs4662750 in MYO7B gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs1057519920 in NFE2L2 gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs11554290 in NRAS gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs10054504 in PDZD2 gene and Renal Cell Carcinoma

PMID 23184150 2013 Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer.

rs104886003 in PIK3CA gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs74911261 in POGLUT3 gene and Renal Cell Carcinoma

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10^-10), 3p22.1 (rs67311347, P=2.5 × 10^-8), 3q26.2 (rs10936602, P=8.8 × 10^-9), 8p21.3 (rs2241261, P=5.8 × 10^-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10^-8), 11q22.3 (rs74911261, P=2.1 × 10^-10) and 14q24.2 (rs4903064, P=2.2 × 10^-24).

rs59294613 in POT1 gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs121909224 in PTEN gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs35252396 in PVT1 gene and Renal Cell Carcinoma

PMID 24220699 2013 A common variant at 8q24.21 is associated with renal cell cancer.

rs1057519949 in RHEB gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs2241261 in RHOBTB2 gene and Renal Cell Carcinoma

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10^-10), 3p22.1 (rs67311347, P=2.5 × 10^-8), 3q26.2 (rs10936602, P=8.8 × 10^-9), 8p21.3 (rs2241261, P=5.8 × 10^-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10^-8), 11q22.3 (rs74911261, P=2.1 × 10^-10) and 14q24.2 (rs4903064, P=2.2 × 10^-24).

rs10484683 in SAMD5 gene and Renal Cell Carcinoma

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

rs4765623 in SCARB1 gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

PMID 21131975 2011 Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

rs755415626 in SF3B1 gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs1057519960 in SF3B2 gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs13027293 in STEAP3 gene and Renal Cell Carcinoma

PMID 31231134 2019 Sex specific associations in genome wide association analysis of renal cell carcinoma.

rs2203002 in TFDP2 gene and Renal Cell Carcinoma

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

rs1057519977 in TP53 gene and Renal Cell Carcinoma

PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs121913346 in VHL gene and Renal Cell Carcinoma

PMID 11921283 2002 Comprehensive mutational analysis of the VHL gene in sporadic renal cell carcinoma: relationship to clinicopathological parameters.

PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

PMID 7660122 1995 Inhibition of transcription elongation by the VHL tumor suppressor protein.

rs12105521 in ZEB2 gene and Renal Cell Carcinoma

PMID 23184150 2013 Common variation at 2q22.3 (ZEB2) influences the risk of renal cancer.

PMID 28598434 2017 Genome-wide association study identifies multiple risk loci for renal cell carcinoma.

PMID 25826619 2015 Common variation at 1q24.1 (ALDH9A1) is a potential risk factor for renal cancer.

rs67311347 in ZNF620 gene and Renal Cell Carcinoma

PMID 28598434 2017 We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10^-10), 3p22.1 (rs67311347, P=2.5 × 10^-8), 3q26.2 (rs10936602, P=8.8 × 10^-9), 8p21.3 (rs2241261, P=5.8 × 10^-9), 10q24.33-q25.1 (rs11813268, P=3.9 × 10^-8), 11q22.3 (rs74911261, P=2.1 × 10^-10) and 14q24.2 (rs4903064, P=2.2 × 10^-24).