Gene: AHR

Alternate names for this Gene: RP85|bHLHe76

Gene Summary: The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes.

Gene is located in Chromosome: 7

Location in Chromosome : 7p21.1

Description of this Gene: aryl hydrocarbon receptor

Type of Gene: protein-coding

Gene: LOC105375170

Alternate names for this Gene:

Gene Summary:

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rs3944100 in AHR;LOC105375170 gene and Carcinoma of lung PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1721043 in AHR;LOC105375170 gene and Vital capacity PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.