rs11610143 in ACVR1B gene and Carcinoma of lung

PMID 26732429 2016 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

rs4886591 in ADAMTS7 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs78062588 in ADAR gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs3944100 in AHR;LOC105375170 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs71658797 in AK5 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs4808075 in BABAM1;USHBP1 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs139789464 in BAG6;APOM gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

PMID 18978787 2008 Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

PMID 19654303 2009 A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.

rs1057519719 in BRAF gene and Carcinoma of lung

PMID 22649091 2012 Kinase-impaired BRAF mutations in lung cancer confer sensitivity to dasatinib.

PMID 21483012 2011 Clinical characteristics of patients with lung adenocarcinomas harboring BRAF mutations.

PMID 19238210 2009 Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines.

PMID 19010912 2008 Genetic predictors of MEK dependence in non-small cell lung cancer.

PMID 12460918 2002 BRAF and RAS mutations in human lung cancer and melanoma.

PMID 23833300 2013 Clinical, pathologic, and biologic features associated with BRAF mutations in non-small cell lung cancer.

PMID 12460919 2002 Missense mutations of the BRAF gene in human lung adenocarcinoma.

PMID 12068308 2002 Mutations of the BRAF gene in human cancer.

PMID 24035431 2013 Lung adenocarcinoma with BRAF G469L mutation refractory to vemurafenib.

PMID 22773810 2012 Lung cancers with acquired resistance to EGFR inhibitors occasionally harbor BRAF gene mutations but lack mutations in KRAS, NRAS, or MEK1.

PMID 22743296 2012 A patient with BRAF V600E lung adenocarcinoma responding to vemurafenib.

PMID 23524406 2013 Molecular characterization of acquired resistance to the BRAF inhibitor dabrafenib in a patient with BRAF-mutant non-small-cell lung cancer.

PMID 21483012 2011 The incidence of BRAF mutations other than V600E is significantly higher in lung cancer than in melanoma.

PMID 22608338 2012 Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: a phase 1 dose-escalation trial.

PMID 25311215 2014 Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cancer/association for molecular pathology guideline.

PMID 23667368 2013 Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group.

PMID 24846033 2014 Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design.

PMID 23562183 2013 Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

PMID 24627688 2014 Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group.

PMID 22798288 2012 BRAF(L597) mutations in melanoma are associated with sensitivity to MEK inhibitors.

rs11571818 in BRCA2 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 24880342 2014 We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs3734542 in BTN2A1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs41266839 in BTN3A1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs35789010 in CARMIL1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1011970 in CDKN2B-AS1 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs10436951 in CEP170 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs17879961 in CHEK2 gene and Carcinoma of lung

PMID 24880342 2014 We identified large-effect genome-wide associations for squamous lung cancer with the rare variants BRCA2 p.Lys3326X (rs11571833, odds ratio (OR) = 2.47, P = 4.74 × 10(-20)) and CHEK2 p.Ile157Thr (rs17879961, OR = 0.38, P = 1.27 × 10(-13)).

rs1051730 in CHRNA3 gene and Carcinoma of lung

PMID 30104567 2018 Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk.

PMID 18978790 2008 Lung cancer susceptibility locus at 5p15.33.

PMID 29924316 2018 Genome-wide association study of familial lung cancer.

PMID 18978787 2008 Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

rs55781567 in CHRNA5 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

PMID 27393504 2016 Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.

rs11639372 in CHRNB4;LOC112268142 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs380286 in CLPTM1L gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

PMID 31009812 2019 Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5_p15.33 TERT-CLPTM1Ll Region.

PMID 18978787 2008 Common 5p15.33 and 6p21.33 variants influence lung cancer risk.

rs148791337 in CROT gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs60280813 in CRTAC1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs12439944 in CSK gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs501942 in CYP21A2;SLC44A4 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs56113850 in CYP2A6 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs9387478 in DCBLD1 gene and Carcinoma of lung

PMID 23143601 2012 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

rs116551911 in DDR1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs2285947 in DNAH11 gene and Carcinoma of lung

PMID 23103227 2012 Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.

rs34517439 in DNAJB4;GIPC2 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1057520037 in EGFR gene and Carcinoma of lung

PMID 16043828 2005 Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib.

rs2741348 in EPHX2;GULOP gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs121913469 in ERBB2 gene and Carcinoma of lung

PMID 15457249 2004 Lung cancer: intragenic ERBB2 kinase mutations in tumours.

rs116165775 in ETAA1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1926203 in FAS;STAMBPL1;ACTA2 gene and Carcinoma of lung

PMID 19654303 2009 Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.

rs11200014 in FGFR2 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs7741164 in FOXP4-AS1 gene and Carcinoma of lung

PMID 26732429 2016 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

rs56084662 in FRY gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs7169304 in GALK2 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1057941 in GBAP1 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs36109883 in H2AC6 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs116822326 in HCP5 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs115729734 in HLA-A gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs115392158 in HLA-B gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs7383287 in HLA-DOB gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs74942078 in HLA-DQA1;HLA-DQA2;LOC107986589 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs2395185 in HLA-DRB9 gene and Carcinoma of lung

PMID 23143601 2012 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

rs12601991 in HNF1B gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs8034191 in HYKK gene and Carcinoma of lung

PMID 19654303 2009 A meta-analysis provided increased support that variation at 15q25.1 (rs8034191; P = 3.24 x 10(-26)), 5p15.33 (rs4975616; P = 2.99 x 10(-9)), and 6p21.33 (rs3117582; P = 4.46 x 10(-10)) influences lung cancer risk.

PMID 18385676 2008 Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1.

PMID 18385738 2008 A susceptibility locus for lung cancer maps to nicotinic acetylcholine receptor subunit genes on 15q25.

PMID 18780872 2008 The risk of lung cancer was more than fivefold higher among those subjects who had both a family history of lung cancer and two copies of high-risk alleles rs8034191 (odds ratio [OR] = 7.20, 95% confidence interval [CI] = 2.21 to 23.37) or rs1051730 (OR = 5.67, CI = 2.21 to 14.60, both of which were located in the 15q24-25.1 locus, than among control subjects.

rs9322193 in KATNA1;RPS18P9 gene and Carcinoma of lung

PMID 27393504 2016 Genome-wide association study confirms lung cancer susceptibility loci on chromosomes 5p15 and 15q25 in an African-American population.

rs11119608 in KCNH1 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs13181 in KLC3;ERCC2 gene and Carcinoma of lung

PMID 23108145 2013 Genome-wide association study reveals novel genetic determinants of DNA repair capacity in lung cancer.

rs121913529 in KRAS gene and Carcinoma of lung

PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

PMID 25044103 2014 Phase II study of the GI-4000 KRAS vaccine after curative therapy in patients with stage I-III lung adenocarcinoma harboring a KRAS G12C, G12D, or G12V mutation.

PMID 23014527 2012 Molecular epidemiology of EGFR and KRAS mutations in 3,026 lung adenocarcinomas: higher susceptibility of women to smoking-related KRAS-mutant cancers.

rs73110464 in KRT8 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs34816374 in LINC00240 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs17181550 in LINC00511 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs144503462 in LINC01347;SEPTIN14P21 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs11692700 in LINC01829;LINC01828 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs35144233 in LMCD1-AS1;LOC101927394 gene and Carcinoma of lung

PMID 29924316 2018 Genome-wide association study of familial lung cancer.

rs753955 in LOC105370113 gene and Carcinoma of lung

PMID 21725308 2011 The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).

rs76980472 in LOC105374786;LINC02831 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs3999544 in LOC105374985;H4C8 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs36162392 in LOC105374988 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs114385935 in LOC105374996;LINC00533 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs139244745 in LOC105375005;LOC101929006 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs185666783 in LOC105377262 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs12201100 in LOC105378031 gene and Carcinoma of lung

PMID 29924316 2018 Genome-wide association study of familial lung cancer.

rs78334599 in LOC107984393 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs75316749 in LOC107986051 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs34158769 in LOC107986582 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs2494938 in LRFN2 gene and Carcinoma of lung

PMID 23103227 2012 Genetic variants at 6p21.1 and 7p15.3 are associated with risk of multiple cancers in Han Chinese.

rs11008347 in MALRD1 gene and Carcinoma of lung

PMID 29924316 2018 Genome-wide association study of familial lung cancer.

rs722864 in MAP3K20 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs71641333 in MGC27382 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs11514963 in MKLN1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs28408315 in MORF4L1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1629083 in MPZL2 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs3131378 in MSH5-SAPCD1;MSH5 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs36600 in MTMR3 gene and Carcinoma of lung

PMID 21725308 2011 The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).

rs2974935 in MTX1 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs115666025 in MUC22 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1419255508 in MXRA5 gene and Carcinoma of lung

PMID 22696596 2012 Exome sequencing identifies MXRA5 as a novel cancer gene frequently mutated in non-small cell lung carcinoma from Chinese patients.

rs481519 in NEK10 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs191205566 in NR4A3;STX17-AS1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs66500423 in NUMBL gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs185038874 in PDS5B gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs121913286 in PIK3CA gene and Carcinoma of lung

PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

rs72981884 in PLIN3 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs116295105 in PPP1R18 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs2233956 in PSORS1C1;C6orf15 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs11844632 in RAD51B gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs10849605 in RAD52 gene and Carcinoma of lung

PMID 22899653 2012 Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls.

rs2300206 in RALY gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs7428320 in RBMS3 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs1057520015 in ROCK1 gene and Carcinoma of lung

PMID 20140017 2010 Activating ROCK1 somatic mutations in human cancer.

rs188586526 in RP1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs7534220 in RTCA-AS1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs13191296 in SCGN gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs189441863 in SDR9C7 gene and Carcinoma of lung

PMID 29924316 2018 Genome-wide association study of familial lung cancer.

rs79040073 in SECISBP2L gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs66759488 in SEMA6D gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs3184504 in SH2B3;ATXN2 gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs28412066 in SLC17A1;SLC17A4 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs121909071 in SLC22A18 gene and Carcinoma of lung

PMID 24846033 2014 Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design.

PMID 24627688 2014 Guideline Recommendations for Testing of ALK Gene Rearrangement in Lung Cancer: A Proposal of the Korean Cardiopulmonary Pathology Study Group.

PMID 23667368 2013 Guideline Recommendations for EGFR Mutation Testing in Lung Cancer: Proposal of the Korean Cardiopulmonary Pathology Study Group.

PMID 23562183 2013 Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

PMID 25311215 2014 Molecular testing for selection of patients with lung cancer for epidermal growth factor receptor and anaplastic lymphoma kinase tyrosine kinase inhibitors: American Society of Clinical Oncology endorsement of the College of American Pathologists/International Association for the study of lung cancer/association for molecular pathology guideline.

rs62621207 in SLF2 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs3794742 in SYNGR2 gene and Carcinoma of lung

PMID 26732429 2016 Meta-analysis of genome-wide association studies identifies multiple lung cancer susceptibility loci in never-smoking Asian women.

rs2918130 in TCERG1L;LOC105378563 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs2187172 in TENM4 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs2736100 in TERT gene and Carcinoma of lung

PMID 23143601 2012 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

PMID 21725308 2011 The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).

PMID 27393504 2016 The association with rs2853677 is driven by the adenocarcinoma subtype of lung cancer (p=1.3×10(-8); OR=1.37; 95% CI=1.23-1.54).

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs748404 in TGM5 gene and Carcinoma of lung

PMID 19654303 2009 Deciphering the impact of common genetic variation on lung cancer risk: a genome-wide association study.

rs7299138 in TMEM132C gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs55902839 in TMEM237 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs144433536 in TNXB gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs139328189 in TP53TG1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs13080835 in TP63 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

PMID 23143601 2012 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

PMID 31009812 2019 Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5_p15.33 TERT-CLPTM1Ll Region.

PMID 21725308 2011 The combined analyses identified six well-replicated SNPs with independent effects and significant lung cancer associations (P < 5.0 × 10(-8)) located in TP63 (rs4488809 at 3q28, P = 7.2 × 10(-26)), TERT-CLPTM1L (rs465498 and rs2736100 at 5p15.33, P = 1.2 × 10(-20) and P = 1.0 × 10(-27), respectively), MIPEP-TNFRSF19 (rs753955 at 13q12.12, P = 1.5 × 10(-12)) and MTMR3-HORMAD2-LIF (rs17728461 and rs36600 at 22q12.2, P = 1.1 × 10(-11) and P = 6.2 × 10(-13), respectively).

rs116418332 in TRIM26 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs11168936 in TUBA1C gene and Carcinoma of lung

PMID 27197191 2016 Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations.

rs7086803 in VTI1A gene and Carcinoma of lung

PMID 23143601 2012 Genome-wide association analysis identifies new lung cancer susceptibility loci in never-smoking women in Asia.

rs4619206 in WNK1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs149866169 in ZNF184;LOC105375001 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs115287935 in ZNF311 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs116480994 in ZNRD1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs34662244 in ZSCAN16-AS1 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs13201681 in ZSCAN23 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs67340775 in ZSCAN31 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs71641308 in ZZZ3 gene and Carcinoma of lung

PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.