Gene: EPHX2

Alternate names for this Gene: ABHD20|CEH|SEH

Gene Summary: This gene encodes a member of the epoxide hydrolase family. The protein, found in both the cytosol and peroxisomes, binds to specific epoxides and converts them to the corresponding dihydrodiols. Mutations in this gene have been associated with familial hypercholesterolemia. Alternatively spliced transcript variants have been described.

Gene is located in Chromosome: 8

Location in Chromosome : 8p21.2-p21.1

Description of this Gene: epoxide hydrolase 2

Type of Gene: protein-coding

Gene: GULOP

Alternate names for this Gene:

Gene Summary:

Gene is located in Chromosome:

Location in Chromosome :

Description of this Gene:

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rs4732728 in EPHX2;GULOP gene and Alzheimer's Disease PMID 29777097 2018 GWAS on family history of Alzheimer's disease.

rs2741348 in EPHX2;GULOP gene and Carcinoma of lung PMID 28604730 2017 Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes.

rs56372821 in EPHX2;GULOP gene and Drug abuse PMID 31209380 2019 Genome-wide association study implicates CHRNA2 in cannabis use disorder.

rs56372821 in EPHX2;GULOP gene and Marijuana Abuse PMID 31209380 2019 Genome-wide association study implicates CHRNA2 in cannabis use disorder.

rs11778040 in EPHX2;GULOP gene and Schizophrenia PMID 30285260 2019 Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

PMID 28991256 2017 Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.

PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.

PMID 25056061 2014 Biological insights from 108 schizophrenia-associated genetic loci.