Gene: FRZB

Alternate names for this Gene: FRE|FRITZ|FRP-3|FRZB-1|FRZB-PEN|FRZB1|FZRB|OS1|SFRP3|SRFP3|hFIZ

Gene Summary: The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility.

Gene is located in Chromosome: 2

Location in Chromosome : 2q32.1

Description of this Gene: frizzled related protein

Type of Gene: protein-coding

rs288326 in FRZB gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 31320639 2019 Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936.

rs1561369 in FRZB gene and Body Height PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7566497 in FRZB gene and Memory, Short-Term PMID 31598132 2019 Genome-Wide Association Study of Latent Cognitive Measures in Adolescence: Genetic Overlap With Intelligence and Education.

rs7775 in FRZB gene and OSTEOARTHRITIS SUSCEPTIBILITY 1 PMID 15210948 2004 Functional variants within the secreted frizzled-related protein 3 gene are associated with hip osteoarthritis in females.