Gene: GGNBP1

Alternate names for this Gene: -

Gene Summary: This gene is the ortholog of the mouse gametogenetin-binding protein 1 gene. In human, the open reading frame is disrupted by a nonsense mutation after 8-aa; consequently, this gene is currently considered to be a unitary pseudogene in human even though it is functional in other mammals.

Gene is located in Chromosome: 6

Location in Chromosome : 6p21.31

Description of this Gene: gametogenetin binding protein 1 (pseudogene)

Type of Gene: pseudo

rs169738 in GGNBP1 gene and Child Development Disorders, Pervasive PMID 28540026 2017 Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.

rs210156 in GGNBP1 gene and Diastolic blood pressure PMID 27841878 2017 Genome-wide association analyses using electronic health records identify new loci influencing blood pressure variation.

rs210131 in GGNBP1 gene and Multiple Sclerosis PMID 26920376 2016 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.

rs169738 in GGNBP1 gene and Platelet Count measurement PMID 29066854 2017 2SNP heritability and effects of genetic variants for neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio.

PMID 29403010 2018 Genetic analysis of quantitative traits in the Japanese population links cell types to complex human diseases.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

PMID 27863252 2016 The Allelic Landscape of Human Blood Cell Trait Variation and Links to Common Complex Disease.

rs169738 in GGNBP1 gene and Schizophrenia PMID 28540026 2017 Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.

PMID 30285260 2019 Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.

PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.

rs210131 in GGNBP1 gene and Systolic Pressure PMID 26920376 2016 Genetic overlap between multiple sclerosis and several cardiovascular disease risk factors.