Gene: IKZF4

Alternate names for this Gene: EOS|ZNFN1A4

Gene Summary: Members of the Ikaros (ZNFN1A1; MIM 603023) family of transcription factors, which includes Eos, are expressed in lymphocytes and are implicated in the control of lymphoid development.[supplied by OMIM, Jul 2002]. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK314543.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2158800 [ECO:0000348] ##Evidence-Data-END##

Gene is located in Chromosome: 12

Location in Chromosome : 12q13.2

Description of this Gene: IKAROS family zinc finger 4

Type of Gene: protein-coding

rs10876864 in IKZF4 gene and Allergic Reaction PMID 29083406 2017 Shared genetic origin of asthma, hay fever and eczema elucidates allergic disease biology.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs10876864 in IKZF4 gene and Asthma PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs10876864 in IKZF4 gene and Intelligence PMID 29326435 2019 A combined analysis of genetically correlated traits identifies 187 loci and a role for neurogenesis and myelination in intelligence.

rs10876864 in IKZF4 gene and Vitiligo PMID 22951725 2013 Association analyses identify three susceptibility Loci for vitiligo in the Chinese Han population.