rs1557055405 in ABCD1 gene and Asthma

PMID 9452087 1998 First missense mutation (W679R) in exon 10 of the adrenoleukodystrophy gene in siblings with adrenomyeloneuropathy.

rs2791189 in ADAMTS14 gene and Asthma

PMID 22694930 2012 Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.

rs4233366 in ADAMTS4 gene and Asthma

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs9866261 in ADAMTS9 gene and Asthma

PMID 26620591 2016 Genome-wide association study in Spanish identifies ADAM metallopeptidase with thrombospondin type 1 motif, 9 (ADAMTS9), as a novel asthma susceptibility gene.

rs114646018 in ADAMTSL1;SAXO1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs12023876 in ADORA1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs17441370 in AKAP6 gene and Asthma

PMID 23181788 2012 HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

rs11123610 in ALLC gene and Asthma

PMID 24792382 2014 Genome-wide association study identifies ALLC polymorphisms correlated with FEV₁ change by corticosteroid.

rs6755248 in AP1S3 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs7104956 in AP2A2 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs73132886 in AP3B1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2476601 in AP4B1-AS1;PTPN22 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs16995986 in ARHGAP24 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs11712165 in ARHGAP31 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs117137535 in ARRDC1 gene and Asthma

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs1555743003 in ASXL3 gene and Asthma

PMID 27075689 2016 Novel splicing mutation in the ASXL3 gene causing Bainbridge-Ropers syndrome.

rs3828309 in ATG16L1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs9372120 in ATG5 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs171165 in ATRN gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs10774625 in ATXN2 gene and Asthma

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs10806425 in BACH2 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs3936215 in BNC2 gene and Asthma

PMID 24406073 2014 Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs182722816 in BTBD11 gene and Asthma

PMID 24406073 2014 Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

rs116020758 in BTNL2;TSBP1-AS1 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs4689355 in C4orf50;JAKMIP1 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs10478040 in CAMK4 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs2479808 in CASC15 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2646928 in CCDC167 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs11635191 in CCDC33 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs130065 in CCHCR1 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs4954192 in CCNT2-AS1;ACMSD gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs13098911 in CCR3 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs3093009 in CCR6 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs1617333 in CD247 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs2514805 in CDH17 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs6959584 in CDHR3 gene and Asthma

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs6908425 in CDKAL1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs12691052 in CETP gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs11778371 in CHRNA2 gene and Asthma

PMID 20698975 2010 Asthma-susceptibility variants identified using probands in case-control and family-based analyses.

PMID 19426955 2009 Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

rs12935657 in CLEC16A gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs114190122 in CLSTN1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs14271 in CLSTN1;PIK3CD gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs74935252 in CMYA5 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs28635831 in COG6 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs2786098 in CRB1 gene and Asthma

PMID 20032318 2010 We observed replication of the association of asthma with SNP rs2786098 in the independent series of persons of European ancestry (combined P=9.3x10(-11)).

rs848512 in CRIM1 gene and Asthma

PMID 23967269 2013 This study found that several new genes might be associated with total IgE in asthmatics, such as CRIM1 (rs848512, P = 1.18×10(-6); rs711254, P = 6.73×10(-6)), ZNF71 (rs10404342, P = 7.60×10(-6)), TLN1 (rs4879926, P = 7.74×10(-6)), and SYNPO2 (rs1472066, P = 8.36×10(-6); rs1038770, P = 8.66×10(-6)).

rs3093059 in CRP gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs16867528 in CTD-2350J17.1;FBXL7 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs34290285 in D2HGDH gene and Asthma

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs3853601 in DDX39B;ATP6V1G2-DDX39B gene and Asthma

PMID 21790008 2011 [Genome-wide association study of allergic diseases in Russians of Western Siberia].

rs1775456 in DENND1B gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs347412 in DGKH gene and Asthma

PMID 25221879 2014 Genome-wide interrogation of longitudinal FEV1 in children with asthma.

rs12451788 in DPH1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs793607 in DUBR gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs11412402 in EEFSEC gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs7918084 in EIF2S2P3 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs61894547 in EMSY gene and Asthma

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs11735820 in EPHA5 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs1058808 in ERBB2 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs2517955 in ERBB2;PGAP3 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs11171739 in ERBB3 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs4673659 in ERBB4 gene and Asthma

PMID 24824216 2014 Genome-wide interaction studies reveal sex-specific asthma risk alleles.

rs58029167 in ERMP1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11221332 in ETS1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs12743520 in EVI5 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs8043253 in EXD1 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs174566 in FADS1;FADS2 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs801429 in FBXL20 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs10044254 in FBXL7 gene and Asthma

PMID 24486069 2014 However, these 3 SNPs were not additionally replicated in the adult asthmatic patients of the remaining trials. rs10044254 lies in the intronic region of F-box and leucine-rich repeat protein 7 (FBXL7) and is associated with decreased expression in immortalized B cells derived from CAMP participants.

rs76684306 in FBXL7;CTD-2350J17.1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2070901 in FCER1G gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs4957798 in FER gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs2301436 in FGFR1OP gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs61816766 in FLG-AS1 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs61816761 in FLG;FLG-AS1 gene and Asthma

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11242168 in FSTL4 gene and Asthma

PMID 21790008 2011 [Genome-wide association study of allergic diseases in Russians of Western Siberia].

rs76506302 in FTCDNL1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs3805236 in GAB1 gene and Asthma

PMID 21804548 2011 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

rs7794356 in GALNT17 gene and Asthma

PMID 26083242 2015 Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma.

rs10905284 in GATA3 gene and Asthma

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs762421 in GATD3A gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs35570272 in GLB1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs75636497 in GLDC gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs517020 in GLT1D1 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs10237103 in GNAI1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs8005161 in GPR65 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs1435547 in GREB1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2353275 in GRID1 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs1007654 in GSDMA gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

rs1008723 in GSDMB gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 24406073 2014 Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

PMID 28461288 2017 A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27439200 2016 Combining genomewide association study and lung eQTL analysis provides evidence for novel genes associated with asthma.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 17611496 2007 Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs2147959 in H2BU1 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs117902240 in HAS2-AS1 gene and Asthma

PMID 28167095 2017 Dust mite allergen exposure modifies the estimated effect of rs117902240 on FEV₁ in children with asthma.

rs114623225 in HCG18;HCG17 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs3117098 in HCG23;TSBP1-AS1 gene and Asthma

PMID 21804548 2011 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

rs2544026 in HDAC7 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs12913832 in HERC2 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs1093 in HLA-B gene and Asthma

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs987870 in HLA-DPA1;HLA-DPB1 gene and Asthma

PMID 21814517 2011 SNP rs987870, located between HLA-DPA1 and HLA-DPB1, was consistently associated with pediatric asthma in 3 independent populations (P(combined) = 2.3×10(-10), odds ratio [OR] = 1.40).

rs3117006 in HLA-DPB2 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs146668528 in HLA-DQA1 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30578877 2019 Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

PMID 23181788 2012 Of these, a common polymorphism (rs9272346) localizing to within 1 Kb of HLA-DQA1 (chromosome 6p21.3) was associated with asthma in adults (P-value = 2.2E-08) with consistent evidence in the more heterogeneous group of adults and children (P-value = 1.0E-04).

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs28383364 in HLA-DQA2;LOC107986589;HLA-DQA1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs201184533 in HLA-DQB1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs9273349 in HLA-DQB1-AS1 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 20860503 2010 We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs9273410 in HLA-DQB1-AS1;HLA-DQB1 gene and Asthma

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

rs2854275 in HLA-DQB1;HLA-DQB1-AS1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs1064713 in HLA-DRB1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs72508457 in HLA-DRB3;HLA-DRB5 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs9268853 in HLA-DRB9 gene and Asthma

PMID 23181788 2012 HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

PMID 30578877 2019 Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

rs12207974 in HLA-E gene and Asthma

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs4675374 in ICOS;LOC101927840 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs4819388 in ICOSLG gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs10445308 in IKZF3 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

PMID 30787307 2019 Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

PMID 28461288 2017 Moreover, we examined whether susceptibility loci identified in previous meta-analyses of GWAS are associated with asthma in Puerto Ricans.The only locus to achieve genome-wide significance was chromosome 17q21, as evidenced by our top single nucleotide polymorphism (SNP), rs907092 (OR 0.71, p=1.2×10^-12) at <i>IKZF3</i> Similar to results in non-Puerto Ricans, SNPs in genes in the same linkage disequilibrium block as <i>IKZF3</i> (<i>e.g.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 24406073 2014 Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

rs10876864 in IKZF4 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs17810546 in IL12A-AS1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs20541 in IL13;TH2LCRR gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs1362348 in IL18R1 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 20860503 2010 We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs10192157 in IL18R1;IL1RL1 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs3755266 in IL18RAP gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs13427957 in IL1R1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs12470864 in IL1RL1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs10173081 in IL1RL1;IL18R1 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 23028483 2012 We also identified two genome-wide significant associations: rs13408661 near IL1RL1/IL18R1 (P(Stage1+Stage2) = 1.1x10(-9)), which is correlated with a variant recently shown to be associated with asthma (rs3771180), and rs9268516 in the HLA region (P(Stage1+Stage2) = 1.1x10(-8)), which appears to be independent of previously reported associations in this locus.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 30578877 2019 Large-scale, multiethnic genome-wide association study identifies novel loci contributing to asthma susceptibility in adults.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11465804 in IL23R gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs12722502 in IL2RA gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs2284033 in IL2RB gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 20860503 2010 We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

rs2066362 in IL33 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

rs142117234 in IL4 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs145986476 in IL4R gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs1986009 in IL5 gene and Asthma

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

rs4129267 in IL6R gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 21907864 2011 Two loci were confirmed to associate with asthma risk in the replication cohorts and reached genome-wide significance in the combined analysis of all available studies (n=57,800): rs4129267 (OR 1·09, combined p=2·4×10(-8)) in the interleukin-6 receptor (IL6R) gene and rs7130588 (OR 1·09, p=1·8×10(-8)) on chromosome 11q13.5 near the leucine-rich repeat containing 32 gene (LRRC32, also known as GARP).

rs6881270 in IL7R gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs1806656 in ILDR1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs1023518 in IRF1-AS1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs9391997 in IRF4 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs11747270 in IRGM gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs4748185 in ITGA8 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs8052139 in ITGAX gene and Asthma

PMID 23040885 2012 Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

rs149317277 in ITGB8 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs2274910 in ITLN1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs1655558 in ITPKA gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs71565398 in ITPR3;LOC105375023;LOC101929188 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs4268898 in ITSN2 gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs4722758 in JAZF1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs75446656 in JMJD1C gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs1597167 in KCNE4 gene and Asthma

PMID 21790008 2011 Two new loci associated with childhood bronchial asthma were identified (20q13.12, rs2425656, P = 1.99 x 10(-7); 1q32.1, rs3817222, rs12734001, P = 2.18 x 10(-7) and 2.79 x 10(-7), respectively) as well as one locus, associated with allergic rhinitis (2q36.1, rs1597167, P = 3.69 x 10(-7)).

rs17729195 in KCNQ5 gene and Asthma

PMID 21790008 2011 [Genome-wide association study of allergic diseases in Russians of Western Siberia].

rs13151961 in KIAA1109 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs113092121 in KIF11 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs77829948 in KIF16B gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs10074523 in KIF3A gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs1061477 in KLK3 gene and Asthma

PMID 23040885 2012 Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

rs936332 in KRT7;KRT7-AS gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs59448276 in KRT86;KRT81 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs3764147 in LACC1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs10174949 in LINC00299 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs10048897 in LINC00528 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs17694970 in LINC00907 gene and Asthma

PMID 21790008 2011 [Genome-wide association study of allergic diseases in Russians of Western Siberia].

rs1684466 in LINC01063 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs111361850 in LINC01091 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2596464 in LINC01149 gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs7506840 in LINC01387 gene and Asthma

PMID 26025128 2015 Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.

rs7281353 in LINC01425 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs115813648 in LINC01527 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs116146467 in LINC01615 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2918302 in LINC01862;LOC107983991 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs1012307 in LINC01931;MMADHC-DT gene and Asthma

PMID 24824216 2014 Genome-wide interaction studies reveal sex-specific asthma risk alleles.

rs13010713 in LINC01934 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs1709393 in LINC02085 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs270636 in LINC02121 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs79252495 in LINC02248;LOC105370740 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs6581895 in LINC02373 gene and Asthma

PMID 29786918 2018 Novel genes and insights in complete asthma remission: A genome-wide association study on clinical and complete asthma remission.

rs11252191 in LINC02660 gene and Asthma

PMID 24406073 2014 Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

rs2844482 in LOC100287329;LTA gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs1736135 in LOC101927745 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs2766664 in LOC101927770 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs13277810 in LOC101927815 gene and Asthma

PMID 30787307 2019 Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

rs75125788 in LOC101928272 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs1214598 in LOC101928512;CD247 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11214966 in LOC101928940 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs149702363 in LOC101929006 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs188610 in LOC101929384;SLC6A12 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs10965947 in LOC101929563 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs3813308 in LOC102723444;TNFAIP8 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs12952581 in LOC102724596 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs350729 in LOC105369165 gene and Asthma

PMID 25562107 2015 Genome-wide association study of short-acting β2-agonists. A novel genome-wide significant locus on chromosome 2 near ASB3.

rs1701704 in LOC105369781;IKZF4 gene and Asthma

PMID 21804548 2011 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

rs9534578 in LOC105370195 gene and Asthma

PMID 24993907 2014 Common genes underlying asthma and COPD? Genome-wide analysis on the Dutch hypothesis.

rs9589866 in LOC105370301 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs74874915 in LOC105370969 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs11645657 in LOC105371081;CLEC16A gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 24388013 2014 The rs62026376:C allele associated with increased asthma with hay fever risk has been found to be associated also with decreased expression of the nearby DEXI gene in monocytes.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

rs12928822 in LOC105371082;RMI2 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs115288876 in LOC105371442 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs79392787 in LOC105371509 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2816316 in LOC105371664 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs9949526 in LOC105372228 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs16841200 in LOC105373710 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs10008032 in LOC105374413 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs4594881 in LOC105374724 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs3116989 in LOC105375021;HLA-DPA3 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs2316527 in LOC105375580;DPP6 gene and Asthma

PMID 26025128 2015 Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.

rs73737676 in LOC105375597 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs1551398 in LOC105375746 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs1425902 in LOC105375836 gene and Asthma

PMID 23967269 2013 A genome-wide association study of total serum and mite-specific IgEs in asthma patients.

rs72716237 in LOC105375999 gene and Asthma

PMID 28167095 2017 Genome-wide interaction study of dust mite allergen on lung function in children with asthma.

rs13314993 in LOC105377022 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs2309284 in LOC105377567 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs1738074 in LOC105378083;LOC107986664;TAGAP gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs11167764 in LOC105378204 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs10789340 in LOC105378797 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs325485 in LOC105379109 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs36080042 in LOC107984238 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs140522418 in LOC107984408 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs917063 in LOC107984695 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs7588010 in LOC107985900;LOC105374811 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs9846423 in LOC107986115 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs28383454 in LOC107986589;HLA-DQA1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs2187668 in LOC107986589;HLA-DQA2;HLA-DQA1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs17167307 in LOC107986770 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs12339348 in LOC107987046;IL33 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs4795403 in LOC112268187;LRRC3C;ORMDL3 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs12603332 in LOC112268187;ORMDL3;LRRC3C gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs12123821 in LOC112268240;FLG-AS1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs643507 in LPIN2;CHORDC1P4 gene and Asthma

PMID 23517042 2013 Genome-wide association study of body mass index in 23 000 individuals with and without asthma.

rs13099273 in LPP gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs1288548 in LRP2BP;LOC107986206 gene and Asthma

PMID 20698975 2010 Asthma-susceptibility variants identified using probands in case-control and family-based analyses.

rs4794820 in LRRC3C gene and Asthma

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs11175593 in LRRK2;LRRK2-DT;LINC02471;LOC105369735 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs3093539 in LTA;LOC100287329 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11971779 in LUC7L2;FMC1-LUC7L2 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs1034395178 in LZTR1 gene and Asthma

PMID 29469822 2018 Autosomal recessive Noonan syndrome associated with biallelic LZTR1 variants.

rs227283 in MANBA gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs4247364 in MAP3K14-AS1;SPATA32 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs12468899 in MAP4K4 gene and Asthma

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

rs146644295 in MED1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11078936 in MED24 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs2855812 in MICB gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11690527 in MIR3681HG gene and Asthma

PMID 22694930 2012 Genome-wide association studies of asthma indicate opposite immunopathogenesis direction from autoimmune diseases.

rs11048317 in MIR4302 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs143326447 in MIR4435-2HG;SOCAR gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs2310300 in MIR4772;IL18RAP gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs9916158 in MIR6884;MED24 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs3190923 in MIR6891;HLA-B gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs6475448 in MLLT3 gene and Asthma

PMID 26083242 2015 Genome-Wide Association Study Identifies Novel Pharmacogenomic Loci For Therapeutic Response to Montelukast in Asthma.

rs3748816 in MMEL1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs115882204 in MPP7-DT;MPP7 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs10835689 in MPPED2-AS1 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs11584383 in MROH3P gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs646356 in MROH7-TTC4;MROH7 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs2052690 in MRVI1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs3197999 in MST1;APEH gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs174535 in MYRF;TMEM258 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs1059513 in NAB2;STAT6 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs7003550 in NCRNA00250 gene and Asthma

PMID 26025128 2015 Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.

rs10699671 in NDFIP1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

rs17064520 in NEDD4L gene and Asthma

PMID 11022011 2000 A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.

rs11172086 in NEMP1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs11190140 in NKX2-3;LINC01475 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs199883290 in NOD2 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs404860 in NOTCH4 gene and Asthma

PMID 21804548 2011 We observed the most significant association with adult asthma at rs404860 in the major histocompatiblity complex region (P = 4.07 × 10(-23)), which is close to rs2070600, a SNP previously reported for association with FEV(1)/FVC in genome-wide association studies for lung function.

rs1293767 in OAS2 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs16894878 in OR12D3;LOC105379641;OR5V1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs8076131 in ORMDL3 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs78894156 in OTOG gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs16903574 in OTULINL gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs10791824 in OVOL1-AS1;OVOL1 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs61741390 in PARD3B gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs204993 in PBX2 gene and Asthma

PMID 21804548 2011 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

rs11684634 in PDE11A gene and Asthma

PMID 20920776 2010 PDE11A associations with asthma: results of a genome-wide association scan.

rs13428806 in PDE11A;PDE11A-AS1 gene and Asthma

PMID 20920776 2010 PDE11A associations with asthma: results of a genome-wide association scan.

rs1544791 in PDE4D gene and Asthma

PMID 19426955 2009 Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.

PMID 20698975 2010 Asthma-susceptibility variants identified using probands in case-control and family-based analyses.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs118079879 in PDZRN4 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs662064 in PEX14 gene and Asthma

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs796051881 in PEX5 gene and Asthma

PMID 26220973 2015 A novel type of rhizomelic chondrodysplasia punctata, RCDP5, is caused by loss of the PEX5 long isoform.

rs12150298 in PGAP3 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs881375 in PHF19 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs276666 in PHF24;FAM205C gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs5758364 in PHF5A gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs4916533 in PIGX;NRROS gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs7224314 in PITPNC1 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs17035378 in PLEK;LOC101927723 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs62344088 in PLEKHG4B gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs2069408 in PMEL;CDK2 gene and Asthma

PMID 21804548 2011 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

rs12965763 in POLI gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs487836 in POLR2M;LOC105370834 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs147121091 in POM121L2 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs12734001 in PPP1R12B gene and Asthma

PMID 21790008 2011 Two new loci associated with childhood bronchial asthma were identified (20q13.12, rs2425656, P = 1.99 x 10(-7); 1q32.1, rs3817222, rs12734001, P = 2.18 x 10(-7) and 2.79 x 10(-7), respectively) as well as one locus, associated with allergic rhinitis (2q36.1, rs1597167, P = 3.69 x 10(-7)).

PMID 21790008 2011 Two new loci associated with childhood bronchial asthma were identified (20q13.12, rs2425656, P = 1.99 x 10(-7); 1q32.1, rs3817222, rs12734001, P = 2.18 x 10(-7) and 2.79 x 10(-7), respectively) as well as one locus, associated with allergic rhinitis (2q36.1, rs1597167, P = 3.69 x 10(-7)).

rs5953283 in PPP1R3F gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs27387 in PRICKLE2 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs281508 in PRKCE gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs943451 in PRKCQ-AS1;PRKCQ gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs7922491 in PRKG1 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs1158867 in PROC gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs12436663 in PRORP gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs10836538 in PRR5L gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs3812141 in PRSS35 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs12453334 in PSMD3 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs3095318 in PSORS1C1;CDSN gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs11788591 in PTGES gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs1893217 in PTPN2 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs17668708 in PTPRC gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs3190930 in PTPRK gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs13003464 in PUS10 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs1101999 in PYHIN1 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs705700 in RAB5B;SUOX gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs2244012 in RAD50 gene and Asthma

PMID 20159242 2010 Multiple SNPs in the RAD50-IL13 region on chromosome 5q31.1 were associated with asthma: rs2244012 in intron 2 of RAD50 (P = 3.04E-07).

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs2040704 in RAD50;TH2LCRR gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 20159242 2010 Genome-wide association study of asthma identifies RAD50-IL13 and HLA-DR/DQ regions.

rs10131490 in RAD51B gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs9895098 in RAP1GAP2 gene and Asthma

PMID 24824216 2014 Genome-wide interaction studies reveal sex-specific asthma risk alleles.

rs7735563 in RAPGEF6 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs11121240 in RERE gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

rs2453626 in RGS22 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs79014439 in RIPOR2 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs1317209 in RNF186 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs115468973 in RNU1-116P gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs146618240 in RNU1-79P gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs10519067 in RORA gene and Asthma

PMID 30787307 2019 Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 27130862 2016 Identification of a new locus at 16q12 associated with time to asthma onset.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs3828058 in RORC gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs3208007 in RTEL1-TNFRSF6B;RTEL1 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs2738783 in RTEL1;RTEL1-TNFRSF6B gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs11088309 in RUNX1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs7517302 in RUNX3 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs742230 in RUNX3;LOC107984932 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs892225 in SBNO2 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs113010607 in SEPTIN8 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs12964116 in SERPINB7 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs12248541 in SH3PXD2A gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs11828343 in SIK2 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs7976838 in SLC16A7 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs2073643 in SLC22A5 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

rs3019885 in SLC30A8 gene and Asthma

PMID 21814517 2011 Genome-wide association study identifies HLA-DP as a susceptibility gene for pediatric asthma in Asian populations.

rs7112383 in SLC5A12 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs2720499 in SLC7A2 gene and Asthma

PMID 26031901 2016 Genome-wide association study of leukotriene modifier response in asthma.

rs10152595 in SMAD3 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

PMID 20860503 2010 We observed associations of genomewide significance between asthma and the following single-nucleotide polymorphisms: rs3771166 on chromosome 2, implicating IL1RL1/IL18R1 (P=3×10(−9)); rs9273349 on chromosome 6, implicating HLA-DQ (P=7×10(−14)); rs1342326 on chromosome 9, flanking IL33 (P=9×10(−10)); rs744910 on chromosome 15 in SMAD3 (P=4×10(−9)); and rs2284033 on chromosome 22 in IL2RB (P=1.1×10(−8)).

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs67551275 in SPSB1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs4653433 in SRP9 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

rs1877031 in STARD3 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs744166 in STAT3 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs167769 in STAT6 gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

PMID 30787307 2019 Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

rs241425 in TAP2 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs114647118 in TATDN1 gene and Asthma

PMID 30787307 2019 Association study in African-admixed populations across the Americas recapitulates asthma risk loci in non-African populations.

rs9896933 in TBCD gene and Asthma

PMID 26025128 2015 We have identified 2 novel tubulin γ pathway SNPs, rs9896933 and rs2074439, showing independent interactive effects with cumulative corticosteroid dose on BMA in children with asthma receiving multiple OCS bursts.

rs62296577 in TBL1XR1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs56308324 in TBX21 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs113612868 in TCAP gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs541559418 in TDRKH gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs908084 in TENM3 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs62623446 in TESPA1 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs11715524 in TFRC gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs115008099 in TH2LCRR;IL13 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 22561531 2012 Genome-wide association study to identify genetic determinants of severe asthma.

rs2240032 in TH2LCRR;RAD50 gene and Asthma

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

rs4833095 in TLR1 gene and Asthma

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

rs28393318 in TLR10 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs148906978 in TLR1;TLR6 gene and Asthma

PMID 29785011 2018 A genome-wide cross-trait analysis from UK Biobank highlights the shared genetic architecture of asthma and allergic diseases.

rs114154155 in TMEM26 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs4574025 in TNFRSF11A gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs4263839 in TNFSF15 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs7518129 in TNFSF4 gene and Asthma

PMID 31036433 2019 Shared and distinct genetic risk factors for childhood-onset and adult-onset asthma: genome-wide and transcriptome-wide studies.

rs1422673 in TNIP1 gene and Asthma

PMID 22694930 2012 Multiple single nucleotide polymorphisms in the TNFAIP3 interacting protein 1 (TNIP1) gene, which interacts with TNFAIP3 and inhibits the TNF-α-induced nuclear factor κB inflammation pathway, were associated with asthma: rs1422673 (P = 3.44 × 10(-7)) and rs10036748 (P = 1.41 × 10(-6), r(2) = 0.67). rs1422673 was also associated with asthma in the published GABRIEL (P = .018) and EVE (P = 1.31 × 10(-5)) studies.

rs76043829 in TNS1 gene and Asthma

PMID 24388013 2014 Single nucleotide polymorphisms with suggestive evidence for association with asthma with hay fever risk included rs41295115 near IL2RA (OR, 1.28; P = 5 × 10(-7)) and rs76043829 in TNS1 (OR, 1.23; P = 2 × 10(-6)).

rs3763309 in TSBP1-AS1;BTNL2 gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs3129943 in TSBP1-AS1;TSBP1 gene and Asthma

PMID 21804548 2011 Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population.

rs10455025 in TSLP gene and Asthma

PMID 29273806 2018 Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks.

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs1887704 in UBAC2 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs272474 in UBE2QL1 gene and Asthma

PMID 23181788 2012 HLA-DQ strikes again: genome-wide association study further confirms HLA-DQ in the diagnosis of asthma among adults.

rs7864027 in UHRF2 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs7169793 in UNC13C gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs7521681 in VAV3 gene and Asthma

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

rs148728975 in VPS13D gene and Asthma

PMID 24406073 2014 Genome-wide association study and admixture mapping identify different asthma-associated loci in Latinos: the Genes-environments & Admixture in Latino Americans study.

rs6736411 in WDPCP gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs1043828 in WDR36 gene and Asthma

PMID 21907864 2011 Identification of IL6R and chromosome 11q13.5 as risk loci for asthma.

rs6982751 in XKR6 gene and Asthma

PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.

rs1672691 in ZBTB16 gene and Asthma

PMID 25918132 2015 Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.

rs7625643 in ZBTB38 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs3741578 in ZBTB39 gene and Asthma

PMID 27611488 2017 Identification of Four Novel Loci in Asthma in European American and African American Populations.

rs2315646 in ZBTB46 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs12447718 in ZFPM1 gene and Asthma

PMID 26025128 2015 Genetic risk factors for decreased bone mineral accretion in children with asthma receiving multiple oral corticosteroid bursts.

rs1460239 in ZFPM2 gene and Asthma

PMID 21790008 2011 [Genome-wide association study of allergic diseases in Russians of Western Siberia].

rs1250552 in ZMIZ1 gene and Asthma

PMID 21150878 2011 Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia.

rs114357009 in ZNF311 gene and Asthma

PMID 31619474 2019 Shared genetics of asthma and mental health disorders: a large-scale genome-wide cross-trait analysis.

rs10995245 in ZNF365;LOC105378327 gene and Asthma

PMID 30929738 2019 Genetic Architectures of Childhood- and Adult-Onset Asthma Are Partly Distinct.

rs12460587 in ZNF432;ZNF841 gene and Asthma

PMID 24280104 2014 Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.

rs2288884 in ZNF614;LOC112268244 gene and Asthma

PMID 24280104 2014 Inhaled corticosteroid treatment modulates ZNF432 gene variant's effect on bronchodilator response in asthmatics.

rs12682865 in ZNF618 gene and Asthma

PMID 23040885 2012 Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.

rs112502960 in ZNF652;LOC102724596 gene and Asthma

PMID 30552067 2019 Moderate-to-severe asthma in individuals of European ancestry: a genome-wide association study.

rs1054609 in ZPBP2 gene and Asthma

PMID 21804549 2011 Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.

PMID 20860503 2010 A large-scale, consortium-based genomewide association study of asthma.

PMID 27182965 2016 Detection and interpretation of shared genetic influences on 42 human traits.

PMID 28461288 2017 A meta-analysis of genome-wide association studies of asthma in Puerto Ricans.