Alternate names for this Gene: C8orf21|C8orf5|C8orf7|XRG6
Gene Summary:
Gene is located in Chromosome: 8
Location in Chromosome : 8p23.1
Description of this Gene: XK related 6
Type of Gene: protein-coding
rs4841465 in
XKR6 gene and
Alcohol consumption
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs6982751 in
XKR6 gene and
Asthma
PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
rs12546366 in
XKR6 gene and
Body Fat Distribution
PMID 30664634 2019 Genome-wide association study of body fat distribution identifies adiposity loci and sex-specific genetic effects.
rs4841504 in
XKR6 gene and
Body mass index
PMID 30239722 2019 Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
rs2898261 in
XKR6 gene and
Eosinophilic esophagitis
PMID 25017104 2014 Genome-wide association analysis of eosinophilic esophagitis provides insight into the tissue specificity of this allergic disease.
rs10096421 in
XKR6 gene and
Glomerular Filtration Rate
PMID 31152163 2019 A catalog of genetic loci associated with kidney function from analyses of a million individuals.
rs6982751 in
XKR6 gene and
Hay fever
PMID 24388013 2014 Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype.
rs11783247 in
XKR6 gene and
Lupus Erythematosus, Systemic
PMID 18204446 2008 Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.
PMID 28714469 2017 Transancestral mapping and genetic load in systemic lupus erythematosus.
PMID 29967481 2018 In conclusion, cSLE is associated with a high cumulative SLE-risk effect and two novel SNPs rs7460469 and rs7300146, providing the first predictive model for cSLE in Koreans.
rs35792458 in
XKR6 gene and
Major Depressive Disorder
PMID 29559929 2018 Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.
rs9969436 in
XKR6 gene and
Mean blood pressure
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs17152930 in
XKR6 gene and
Non-Small Cell Lung Carcinoma
PMID 21866343 2012 The 18p11.22 locus is associated with never smoker non-small cell lung cancer susceptibility in Korean populations.
rs149776388 in
XKR6 gene and
Schizophrenia
PMID 27846195 2017 Genome-wide association study of paliperidone efficacy.
rs11779675 in
XKR6 gene and
Smoking
PMID 30643258 2019 Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences.
rs10107145 in
XKR6 gene and
Systolic Pressure
PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs4841465 in
XKR6 gene and
Systolic blood pressure measurement
PMID 29912962 2018 Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
rs7819412 in
XKR6 gene and
Triglycerides measurement
PMID 19060906 2009 Common variants at 30 loci contribute to polygenic dyslipidemia.
rs35792458 in
XKR6 gene and
Unipolar Depression
PMID 29559929 2018 Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.
rs35792458 in
XKR6 gene and
response to SSRI
PMID 29559929 2018 Association of the Polygenic Scores for Personality Traits and Response to Selective Serotonin Reuptake Inhibitors in Patients with Major Depressive Disorder.