Gene: IL1RAP

Alternate names for this Gene: C3orf13|IL-1RAcP|IL1R3

Gene Summary: This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress.

Gene is located in Chromosome: 3

Location in Chromosome : 3q28

Description of this Gene: interleukin 1 receptor accessory protein

Type of Gene: protein-coding

rs34879831 in IL1RAP gene and Blood Protein Measurement PMID 29875488 2018 Genomic atlas of the human plasma proteome.

PMID 30072576 2018 Co-regulatory networks of human serum proteins link genetics to disease.

rs10433493 in IL1RAP gene and Low density lipoprotein cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

rs3773986 in IL1RAP gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.

rs10433493 in IL1RAP gene and Serum LDL cholesterol measurement PMID 23063622 2012 Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.