Condition: Mucocutaneous Lymph Node Syndrome


rs2293256 in ATP5MF;ATP5MF-PTCD1;PTCD1 gene and Mucocutaneous Lymph Node Syndrome PMID 23677057 2013 Identification of KCNN2 as a susceptibility locus for coronary artery aneurysms in Kawasaki disease using genome-wide association analysis.

rs10100215 in BLK gene and Mucocutaneous Lymph Node Syndrome PMID 22446962 2012 A genome-wide association study identifies three new risk loci for Kawasaki disease.

rs17161726 in BUD31 gene and Mucocutaneous Lymph Node Syndrome PMID 23677057 2013 Identification of KCNN2 as a susceptibility locus for coronary artery aneurysms in Kawasaki disease using genome-wide association analysis.

rs2130392 in CENPU gene and Mucocutaneous Lymph Node Syndrome PMID 22446962 2012 A genome-wide association study identifies three new risk loci for Kawasaki disease.

rs527409 in DAB1 gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 Of these, one locus on chromosome 1p31 (rs527409) was replicated in 266 children with KD and 600 normal controls (odds ratio [OR] = 2.90, 95% confidence interval [CI] = 1.85-4.54, P (combined) = 1.46 × 10(-6)); and a PELI1 locus on chromosome 2p13.3 (rs7604693) was replicated in 86 KD patients with CALs and 600 controls (OR = 2.70, 95% CI = 1.77-4.12, P (combined) = 2.00 × 10(-6)).

rs1801274 in FCGR2A gene and Mucocutaneous Lymph Node Syndrome PMID 22081228 2011 Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease.

PMID 28886140 2017 The present study demonstrates that p.His167Arg, a KD-associated FCGR2A variant, acts as a susceptibility gene in males only.

rs10127456 in FHAD1;FHAD1-AS1 gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.

rs3129871 in HLA-DRA gene and Mucocutaneous Lymph Node Syndrome PMID 22446962 2012 A genome-wide association study identifies three new risk loci for Kawasaki disease.

rs3773986 in IL1RAP gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.

rs7185022 in IRF8 gene and Mucocutaneous Lymph Node Syndrome PMID 22446961 2012 Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.

rs28493229 in ITPKC;COQ8B gene and Mucocutaneous Lymph Node Syndrome PMID 22081228 2011 Genome-wide association study identifies FCGR2A as a susceptibility locus for Kawasaki disease.

rs10082659 in LDLRAD3 gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.

rs17136627 in LOC101927078;KCNN2 gene and Mucocutaneous Lymph Node Syndrome PMID 23677057 2013 Of these, an SNP (rs17136627) in the potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2 (KCNN2) at 5q22.3 was validated in 32 KD patients with large aneurysms (diameter>5 mm) and 191 KD patients without CALs (odds ratio (OR)=12.6, P(combined)=1.96 × 10(-8)).

rs16921209 in LOC102725112;NEBL gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Upon our previous genotyping data of 157 valid KD subjects, a genome-wide association study (GWAS) has been conducted among 11 (7%) CAA-developed KD patients to reveal five significant genetic variants passed pre-defined thresholds and resulted in two novel susceptibility protein-coding genes, which are NEBL (rs16921209 (P = 7.44 × 10(-9); OR = 32.22) and rs7922552 (P = 8.43 × 10(-9); OR = 32.0)) and TUBA3C (rs17076896 (P = 8.04 × 10(-9); OR = 21.03)).

rs456290 in LOC105377673;SGCD gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.

rs1877672 in LOC107986926 gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.

rs12210919 in MDGA1 gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.

rs17667932 in MED30 gene and Mucocutaneous Lymph Node Syndrome PMID 22446961 2012 Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.

rs12900413 in MESP2 gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.

rs2233152 in MIA;MIA-RAB4B gene and Mucocutaneous Lymph Node Syndrome PMID 22446962 2012 A genome-wide association study identifies three new risk loci for Kawasaki disease.

rs17531088 in NAALADL2 gene and Mucocutaneous Lymph Node Syndrome PMID 19132087 2009 Significant associations of 40 SNPs and six haplotypes, identifying 31 genes, were replicated in an independent cohort of 583 predominantly Caucasian KD families, with NAALADL2 (rs17531088, p(combined) = 1.13 x 10(-6)) and ZFHX3 (rs7199343, p(combined) = 2.37 x 10(-6)) most significantly associated.

rs6012536 in PREX1 gene and Mucocutaneous Lymph Node Syndrome PMID 21221998 2011 A genome-wide association analysis reveals 1p31 and 2p13.3 as susceptibility loci for Kawasaki disease.

rs17782904 in SETBP1 gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.

rs3762491 in SLC35F5 gene and Mucocutaneous Lymph Node Syndrome PMID 23677057 2013 Identification of KCNN2 as a susceptibility locus for coronary artery aneurysms in Kawasaki disease using genome-wide association analysis.

rs7656244 in TECRL gene and Mucocutaneous Lymph Node Syndrome PMID 22446961 2012 Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.

rs17076896 in TUBA3C;LOC101928697 gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Upon our previous genotyping data of 157 valid KD subjects, a genome-wide association study (GWAS) has been conducted among 11 (7%) CAA-developed KD patients to reveal five significant genetic variants passed pre-defined thresholds and resulted in two novel susceptibility protein-coding genes, which are NEBL (rs16921209 (P = 7.44 × 10(-9); OR = 32.22) and rs7922552 (P = 8.43 × 10(-9); OR = 32.0)) and TUBA3C (rs17076896 (P = 8.04 × 10(-9); OR = 21.03)).

rs11793049 in ZNF618 gene and Mucocutaneous Lymph Node Syndrome PMID 27171184 2016 Genome-Wide Association Study Identifies Novel Susceptibility Genes Associated with Coronary Artery Aneurysm Formation in Kawasaki Disease.

rs11734 in ZSCAN25 gene and Mucocutaneous Lymph Node Syndrome PMID 23677057 2013 Identification of KCNN2 as a susceptibility locus for coronary artery aneurysms in Kawasaki disease using genome-wide association analysis.