Gene: RTKN2

Alternate names for this Gene: PLEKHK1|bA531F24.1

Gene Summary:

Gene is located in Chromosome: 10

Location in Chromosome : 10q21.2

Description of this Gene: rhotekin 2

Type of Gene: protein-coding

rs66964413 in RTKN2 gene and Breast Carcinoma PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.

rs10821967 in RTKN2 gene and Cardiovascular Diseases PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs7923556 in RTKN2 gene and Colorectal Carcinoma PMID 24448986 2014 Genome-wide association study identifies a new SMAD7 risk variant associated with colorectal cancer risk in East Asians.

rs10995092 in RTKN2 gene and Lupus Erythematosus, Systemic PMID 26502338 2015 Genetic association analyses implicate aberrant regulation of innate and adaptive immunity genes in the pathogenesis of systemic lupus erythematosus.

rs3125734 in RTKN2 gene and Rheumatoid Arthritis PMID 23028356 2012 Functional variants in NFKBIE and RTKN2 involved in activation of the NF-κB pathway are associated with rheumatoid arthritis in Japanese.

rs79193624 in RTKN2 gene and Schizophrenia PMID 26198764 2015 Genome-wide association study of schizophrenia in Ashkenazi Jews.