Gene: ZC3H11A

Alternate names for this Gene: ZC3HDC11A

Gene Summary:

Gene is located in Chromosome: 1

Location in Chromosome : 1q32.1

Description of this Gene: zinc finger CCCH-type containing 11A

Type of Gene: protein-coding

Gene: ZBED6

Alternate names for this Gene: MGR

Gene Summary: The protein encoded by this transposon-derived intronless gene is a transcriptional repressor that binds to the consensus sequence 5'-GCTCGC-3'. The encoded protein has been shown to repress IGF2 transcription. This gene is located within the first intron of the ZC3H11A gene.

Gene is located in Chromosome: 1

Location in Chromosome : 1q32.1

Description of this Gene: zinc finger BED-type containing 6

Type of Gene: protein-coding

rs116315504 in ZC3H11A;ZBED6 gene and Alopecia PMID 28196072 2017 Genetic prediction of male pattern baldness.

rs4951011 in ZC3H11A;ZBED6 gene and Breast Carcinoma PMID 25038754 2014 In a three-stage genome-wide association study among East Asian women including 22,780 cases and 24,181 controls, we identified 3 genetic loci newly associated with breast cancer risk, including rs4951011 at 1q32.1 (in intron 2 of the ZC3H11A gene; P=8.82×10(-9)), rs10474352 at 5q14.3 (near the ARRDC3 gene; P=1.67×10(-9)) and rs2290203 at 15q26.1 (in intron 14 of the PRC1 gene; P=4.25×10(-8)).

PMID 29059683 2017 Association analysis identifies 65 new breast cancer risk loci.

rs61827266 in ZC3H11A;ZBED6 gene and RDW - Red blood cell distribution width result PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.

rs61827266 in ZC3H11A;ZBED6 gene and Red cell distribution width determination PMID 30595370 2019 Leveraging Polygenic Functional Enrichment to Improve GWAS Power.