Variant: rs104894226 

    present in Gene: LRRC56;HRAS
    present in Chromosome: 11
    Position on Chromosome: 534285
    Alleles of this Variant: C/A;G;T

rs104894226 in LRRC56;HRAS gene and Adenocarcinoma of lung (disorder) PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Adenocarcinoma of pancreas PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Alopecia PMID 16170316 2005 Germline mutations in HRAS proto-oncogene cause Costello syndrome.

rs104894226 in LRRC56;HRAS gene and Cardiomyopathies, Primary PMID 16170316 2005 Germline mutations in HRAS proto-oncogene cause Costello syndrome.

rs104894226 in LRRC56;HRAS gene and Chronic Lymphocytic Leukemia PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Colorectal Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Costello syndrome (disorder) PMID 18039947 2008 Severe neonatal manifestations of Costello syndrome.

PMID 16170316 2005 Germline mutations in HRAS proto-oncogene cause Costello syndrome.

PMID 24224811 2013 Kinetic mechanisms of mutation-dependent Harvey Ras activation and their relevance for the development of Costello syndrome.

PMID 17054105 2007 Diversity, parental germline origin, and phenotypic spectrum of de novo HRAS missense changes in Costello syndrome.

PMID 25173338 2014 2014 ESC Guidelines on diagnosis and management of hypertrophic cardiomyopathy: the Task Force for the Diagnosis and Management of Hypertrophic Cardiomyopathy of the European Society of Cardiology (ESC).

PMID 19995790 2010 Duplication of Glu37 in the switch I region of HRAS impairs effector/GAP binding and underlies Costello syndrome by promoting enhanced growth factor-dependent MAPK and AKT activation.

PMID 16329078 2006 HRAS mutation analysis in Costello syndrome: genotype and phenotype correlation.

PMID 18247425 2008 Costello syndrome associated with novel germline HRAS mutations: an attenuated phenotype?

PMID 16443854 2006 Genotype-phenotype correlation in Costello syndrome: HRAS mutation analysis in 43 cases.

rs104894226 in LRRC56;HRAS gene and Cutaneous Melanoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Facial wart PMID 16170316 2005 Germline mutations in HRAS proto-oncogene cause Costello syndrome.

rs104894226 in LRRC56;HRAS gene and Gastric Adenocarcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Global developmental delay PMID 16170316 2005 Germline mutations in HRAS proto-oncogene cause Costello syndrome.

rs104894226 in LRRC56;HRAS gene and Leukemia, Myelocytic, Acute PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Liver carcinoma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Malignant Uterine Corpus Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Mammary Neoplasms PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Multiple Myeloma PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Palmoplantar Keratosis PMID 16170316 2005 Germline mutations in HRAS proto-oncogene cause Costello syndrome.

rs104894226 in LRRC56;HRAS gene and Squamous cell carcinoma of lung PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Squamous cell carcinoma of skin PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Squamous cell carcinoma of the head and neck PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Thymoma PMID 25157968 2014 Prospective enterprise-level molecular genotyping of a cohort of cancer patients.

PMID 20859122 2010 Thymic tumors: relevant molecular data in the clinic.

rs104894226 in LRRC56;HRAS gene and Transitional cell carcinoma of bladder PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.

rs104894226 in LRRC56;HRAS gene and Uterine Cervical Neoplasm PMID 26619011 2016 Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity.