present in Gene: ATP2B1
present in Chromosome: 12
Position on Chromosome: 89666809
Alleles of this Variant: G/A
rs17249754 in
ATP2B1 gene and
Blood Pressure
PMID 21572416 2011 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
PMID 24001895 2013 Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.
PMID 21909110 2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
rs17249754 in
ATP2B1 gene and
Diastolic blood pressure
PMID 21572416 2011 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
PMID 29455858 2018 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
PMID 26390057 2015 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
rs17249754 in
ATP2B1 gene and
Hypertensive disease
PMID 31513605 2019 Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes.
PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
rs17249754 in
ATP2B1 gene and
Mean blood pressure
PMID 26390057 2015 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
PMID 24001895 2013 Genome-wide association study meta-analysis reveals transethnic replication of mean arterial and pulse pressure loci.
PMID 21909110 2011 Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure.
rs17249754 in
ATP2B1 gene and
Systolic Pressure
PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.
PMID 19396169 2009 For systolic blood pressure, the most compelling association involved chromosome 12q21 and variants near the ATP2B1 gene (rs17249754, P = 1.3 x 10(-7)).
PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.
PMID 21572416 2011 Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.
PMID 26390057 2015 Trans-ancestry genome-wide association study identifies 12 genetic loci influencing blood pressure and implicates a role for DNA methylation.
PMID 29455858 2018 A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.
PMID 28739976 2017 Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets From Blood and the Kidney.
rs17249754 in
ATP2B1 gene and
Systolic blood pressure measurement
PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.
rs17249754 in
ATP2B1 gene and
Waist-Hip Ratio
PMID 19396169 2009 A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits.