rs3768939 in AGAP1 gene and Hypertensive disease

PMID 26516778 2015 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.

rs2992257 in APBB1IP gene and Hypertensive disease

PMID 22566498 2012 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

rs429358 in APOE gene and Hypertensive disease

PMID 31055733 2019 Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.

rs604723 in ARHGAP42 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs11105364 in ATP2B1 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

PMID 28273873 2017 Interaction between Single Nucleotide Polymorphism and Urinary Sodium, Potassium, and Sodium-Potassium Ratio on the Risk of Hypertension in Korean Adults.

PMID 31513605 2019 Structural equation modeling for hypertension and type 2 diabetes based on multiple SNPs and multiple phenotypes.

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

PMID 19430479 2009 Genome-wide association study of blood pressure and hypertension.

rs805303 in BAG6 gene and Hypertensive disease

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs4409766 in BORCS7-ASMT;BORCS7 gene and Hypertensive disease

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs28404156 in BST1 gene and Hypertensive disease

PMID 31423876 2019 Genome-Wide Meta-Analysis of Blood Pressure Response to β₁-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies).

rs12715461 in CACNA1D gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs11014166 in CACNB2 gene and Hypertensive disease

PMID 19430479 2009 Genome-wide association study of blood pressure and hypertension.

rs10745332 in CAPZA1 gene and Hypertensive disease

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs12046278 in CASZ1 gene and Hypertensive disease

PMID 31545351 2019 The known hypertension locus, CASZ1, was a top finding among EAs (P = 1.1 × 10-8) and in the race-combined analysis (P = 1.5 × 10-9) using the normotensive control group (rs12046278, odds ratio = 0.71 (95% confidence interval: 0.6-0.8)).

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs115236533 in CDH18 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs1333047 in CDKN2B-AS1 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs7302981 in CERS5 gene and Hypertensive disease

PMID 27618448 2016 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs11191548 in CNNM2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs79105258 in CUX2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs12679242 in CYP11B2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs1004467 in CYP17A1;CYP17A1-AS1 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs16962897 in DNAAF1 gene and Hypertensive disease

PMID 27802415 2017 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

rs1126464 in DPEP1 gene and Hypertensive disease

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs790116 in EIF4BP8 gene and Hypertensive disease

PMID 22566498 2012 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

rs17046380 in EML6 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs10033366 in ENPEP gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs2521501 in FES gene and Hypertensive disease

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs5006548 in FGD4 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs12630213 in FGD5 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

PMID 31217584 2019 Genetic analyses of diverse populations improves discovery for complex traits.

rs17004869 in FGF5 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs115795127 in FRMD3 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs6596140 in FSTL4 gene and Hypertensive disease

PMID 22384028 2012 Using a family-based association test, we found an association with SNPs on chromosome 5q31.1 (rs6596140; P<9 × 10(-8)) for hypertension.

rs17514846 in FURIN gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs62525059 in GML gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs6418 in GML;CYP11B2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs78192203 in GPR20 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs10188442 in GPR39 gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs13143871 in GUCY1A1 gene and Hypertensive disease

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

rs11066280 in HECTD4 gene and Hypertensive disease

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

rs9943291 in HMGCS2 gene and Hypertensive disease

PMID 29523524 2018 Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.

rs1859168 in HOTTIP gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs2067087 in HOTTIP;HOXA13 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs6969780 in HOXA-AS2;HOXA3 gene and Hypertensive disease

PMID 27618448 2016 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs6461992 in HOXA10-HOXA9;HOXA11;HOXA10 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs7406910 in HOXB7 gene and Hypertensive disease

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs1565930588 in HSPB8 gene and Hypertensive disease

PMID 28501893 2017 HSPB8 haploinsufficiency causes dominant adult-onset axial and distal myopathy.

PMID 26976520 2016 Mutations in HSPB8 causing a new phenotype of distal myopathy and motor neuropathy.

PMID 29029362 2018 Altered TDP-43-dependent splicing in HSPB8-related distal hereditary motor neuropathy and myofibrillar myopathy.

rs13353058 in IKZF5;PSTK gene and Hypertensive disease

PMID 21082022 2010 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

rs1275988 in KCNK3 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs4665630 in KLHL29 gene and Hypertensive disease

PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

rs403814 in L3MBTL4 gene and Hypertensive disease

PMID 27480026 2016 Four single nucleotide polymorphisms (SNPs) at three new genes (L3MBTL4 rs403814, Pmeta = 6.128 × 10(-9); LOC729251, and TCEANC) and seven SNPs at five previously reported genes were identified as being significantly associated with hypertension.

rs61824877 in LINC00862 gene and Hypertensive disease

PMID 29523524 2018 Genome Wide Association Study Identifies the HMGCS2 Locus to be Associated With Chlorthalidone Induced Glucose Increase in Hypertensive Patients.

rs9907379 in LINC02875 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs7168353 in LOC101927025 gene and Hypertensive disease

PMID 22566498 2012 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

rs11977526 in LOC102723446 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs1925458 in LOC102724749;LOC105374976 gene and Hypertensive disease

PMID 31055733 2019 Genetic heterogeneity of Alzheimer's disease in subjects with and without hypertension.

rs10785581 in LOC105369743 gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs11067763 in LOC105370003 gene and Hypertensive disease

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

rs6978712 in LOC105375490 gene and Hypertensive disease

PMID 25317111 2014 Genome-wide association study of medication adherence in chronic diseases in the korean population.

rs6536088 in LOC105377506 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs4905794 in LOC107984696 gene and Hypertensive disease

PMID 29973135 2018 The association of rs4905794 did not significantly replicate, even though in DYNAMIC the effect was in the same direction (β = - 0.8%, P = 0.4 for systolic and β = - 1.6%, P = 0.13 for diastolic night-to-day BP ratio).

rs151344517 in LOC107985154;AFG3L2;TUBB6 gene and Hypertensive disease

PMID 20725928 2010 Missense mutations in the AFG3L2 proteolytic domain account for ∼1.5% of European autosomal dominant cerebellar ataxias.

rs200759 in LOC107985394;MACROD2 gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs1799945 in LOC108783645;HFE gene and Hypertensive disease

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs11230728 in LRRC10B gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs2226284 in LRRC7 gene and Hypertensive disease

PMID 22322875 2012 Genetic association of short sleep duration with hypertension incidence--a 6-year follow-up in the Korean genome and epidemiology study.

rs1973765 in LSP1 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs1027989 in LYN gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs200752 in MACROD2 gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs28403420 in MICALL2 gene and Hypertensive disease

PMID 31545351 2019 Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group.

rs12129649 in MOV10 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs3798440 in MYO6 gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs8101673 in MYO9B gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs11537751 in NDUFS3;PTPMT1;CELF1 gene and Hypertensive disease

PMID 27618448 2016 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

rs6021247 in NFATC2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs891511 in NOS3 gene and Hypertensive disease

PMID 27618448 2016 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

rs11191580 in NT5C2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs11229457 in OR5B12 gene and Hypertensive disease

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs9791170 in P4HA2 gene and Hypertensive disease

PMID 19609347 2009 No variant reached genome wide significance for association with diastolic BP (top scoring SNP rs1867226, p = 5.8 x 10(-7)) or with hypertension as a binary trait (top scoring SNP rs9791170, p = 5.1 x 10(-7)).

rs66978877 in PGPEP1 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs932764 in PLCE1 gene and Hypertensive disease

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs62434120 in PLEKHG1 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs11124945 in PLEKHH2 gene and Hypertensive disease

PMID 27670767 2018 Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.

rs659580 in PRRX1 gene and Hypertensive disease

PMID 22566498 2012 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

rs28933386 in PTPN11 gene and Hypertensive disease

PMID 11704759 2001 Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome.

PMID 16358218 2006 Diversity and functional consequences of germline and somatic PTPN11 mutations in human disease.

rs35529250 in RBM47 gene and Hypertensive disease

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs167479 in RGL3 gene and Hypertensive disease

PMID 27618448 2016 Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci.

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs139293840 in RPTOR gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs137852704 in SCNN1B gene and Hypertensive disease

PMID 27900368 2016 Whole-exome sequencing reveals an inherited R566X mutation of the epithelial sodium channel β-subunit in a case of early-onset phenotype of Liddle syndrome.

rs115706913 in SGCZ gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

PMID 27802415 2017 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

rs7801190 in SLC12A9 gene and Hypertensive disease

PMID 21347282 2011 Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.

rs16896398 in SLC22A7 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs2270860 in SLC22A7;CRIP3 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs13107325 in SLC39A8 gene and Hypertensive disease

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.

rs4686340 in SRGAP3 gene and Hypertensive disease

PMID 22384028 2012 A genome-wide linkage and association scan reveals novel loci for hypertension and blood pressure traits.

rs186208701 in STK3 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs4387287 in STN1 gene and Hypertensive disease

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs2649044 in SWAP70 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs4150161 in TAF1C gene and Hypertensive disease

PMID 27802415 2017 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

rs76987554 in TARID gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs2240736 in TBX2 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

rs4833103 in TLR1 gene and Hypertensive disease

PMID 27670767 2018 Genome-wide association study identifies pharmacogenomic loci linked with specific antihypertensive drug treatment and new-onset diabetes.

rs3913363 in TMEM212;LOC105374218 gene and Hypertensive disease

PMID 22566498 2012 Genomic association analysis identifies multiple loci influencing antihypertensive response to an angiotensin II receptor blocker.

rs2021783 in TNXB gene and Hypertensive disease

PMID 25249183 2015 Genome-wide association study in Chinese identifies novel loci for blood pressure and hypertension.

rs7372217 in ULK4 gene and Hypertensive disease

PMID 28498854 2017 Single-trait and multi-trait genome-wide association analyses identify novel loci for blood pressure in African-ancestry populations.

rs13333226 in UMOD gene and Hypertensive disease

PMID 21082022 2010 In a subset of 13,446 individuals with estimated glomerular filtration rate (eGFR) measurements, we show that rs13333226 is independently associated with hypertension (unadjusted for eGFR: 0.89 [0.83-0.96], p = 0.004; after eGFR adjustment: 0.89 [0.83-0.96], p = 0.003).

PMID 27618447 2016 Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension.

PMID 21082022 2010 Genome-wide association study of blood pressure extremes identifies variant near UMOD associated with hypertension.

rs28495639 in USP8 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs10776752 in WNT2B gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs6452524 in XRCC4 gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs6506537 in YES1 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs11784910 in ZDHHC2 gene and Hypertensive disease

PMID 27802415 2017 Genome-Wide and Gene-Based Meta-Analyses Identify Novel Loci Influencing Blood Pressure Response to Hydrochlorothiazide.

rs1372662 in ZFAT gene and Hypertensive disease

PMID 21626137 2011 Two-marker association tests yield new disease associations for coronary artery disease and hypertension.

rs10948071 in ZNF318 gene and Hypertensive disease

PMID 30487518 2018 Interethnic analyses of blood pressure loci in populations of East Asian and European descent.

rs16964543 in ZNF536 gene and Hypertensive disease

PMID 26516778 2015 Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium.

rs16982520 in ZNF831 gene and Hypertensive disease

PMID 19430479 2009 Genome-wide association study of blood pressure and hypertension.

PMID 21909115 2011 Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.