A hazard ratio is the probability of an adverse event occurring in the disease group in comparison with an event occurring in the control group. The genetic markers analyzed for Breast Cancer prognosis are different from that analyzed for the risk of onset of Breast Cancer.
In the event that a person has breast cancer, hazard ratio describes the probability of how severe the prognosis of breast cancer may be.
Thus, even if the genetic risk for breast cancer is low, the hazard ratio score for the prognosis can be high.
Please note that only a qualified physician should interpret the prognosis, based on both genetic as well as non genetic factors