Q: How can this report help me understand my breast cancer risk?

A: The BRCA and Breast Cancer Report provides insights into your genetic predispositions related to breast cancer, including the presence of BRCA1 and BRCA2 gene mutations. Understanding these genetic factors can help you take proactive steps for early detection, preventive measures, and personalized healthcare planning.

Q: What are the FDA-approved BRCA markers?

A: The FDA-approved BRCA markers are specific genetic variants that have been validated by the Food and Drug Administration for use in genetic screening for breast and ovarian cancer risk. These markers are used to identify individuals who have a higher genetic predisposition to these cancers. The approved markers include variants such as rs386833395, rs80357906, and rs80359550.*

*More markers have now been approved by the FDA for breast cancer risk reporting, which will be included in the report with the next update.

Q: What should I make out of the pharmacogenetics of breast cancer section in my report?

A: The pharmacogenetics section provides information on how your genetic makeup can influence your response to various breast cancer treatments. This includes your likely response to specific chemotherapy drugs, potential side effects, and effectiveness of treatments. This information can help your healthcare provider tailor your treatment plan to optimize efficacy and minimize adverse effects.

Q: What lifestyle factors are analyzed in relation to breast cancer risk?

A: The report analyzes the impact of various lifestyle factors on breast cancer risk, including:

• Alcohol consumption
• Smoking
• Radiation exposure
• Exercise levels
• Smoked meat consumption
• Menopausal hormone therapy
• Shift work
• Body weight

Q: If BRCA markers are identified, will I definitely get breast cancer?

A: Testing positive for BRCA mutations indicates a higher risk of developing breast cancer, but it does not mean you will definitely get cancer. Many individuals with BRCA mutations never develop the disease. Your actual risk depends on multiple factors, including lifestyle, environment, and other genetic factors. It is important to discuss your results with a healthcare professional to understand your risk and explore preventive options.

Q: What steps should I take if my report shows a high risk for breast cancer?

A: If your report shows a high genetic risk for breast cancer, consider the following steps:

• Consult with a genetic counselor or healthcare provider to discuss your results.
• Follow recommended screening guidelines, such as regular mammograms or MRI scans.
• Consider lifestyle changes to reduce risk factors, such as maintaining a healthy weight, limiting alcohol consumption, and avoiding smoking.
• Discuss potential preventive measures, such as prophylactic surgery or medication, with your healthcare provider.

Q: How long will it take to receive my results after submitting my DNA data?

A: After uploading your DNA data, the report is typically generated and shared with you via email within 12-24 hours.

Q: How is my genetic information kept secure?

A: Your privacy is our top priority. We adhere to strict protocols to ensure your genetic data and personal information are kept secure and confidential. Your data is never shared with third parties without your explicit consent.

Q: What if I don’t have my DNA data yet?

A: You can place your order now and upload your DNA data anytime. There’s no time limit on when you can upload the data. DNA data can be obtained through any genetic test on the market. Popular options include MyHeritageDNA, AncestryDNA, and 23andMe. Xcode Life is not affiliated with any of these companies.