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May 4, 2017
Know Your Genes: GABPB1 “ The Energy Gene”

GA‐binding protein (GABP) transcription factor gene, also known as the Nuclear Respiratory Factor 2 (NRF2) gene is associated with the synthesis of GABPB1, a key transcriptional activator of numerous nuclear genes which produce various mitochondrial enzymes. The variants of the GABPB1 gene that code for the beta1 subunit of NRF2 protein have been shown to […]

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April 25, 2017
ACE Gene: The Key To A Fit And Healthy Lifestyle!

ACE gene: An introduction ACE gene codes for Angiotensin-Converting Enzyme. This enzyme is a part of the Renin-Angiotensin System, which is responsible for maintaining blood pressure, and fluid and salt balance in the body. The enzyme cleaves the protein angiotensin I at a particular site, converting it into angiotensin II. This angiotensin II brings about […]

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April 5, 2017
Know Your Genes: PPARA

The Peroxisome Proliferator- Activated Receptor (PPARA) gene is associated with the synthesis of Peroxisome Proliferator- Activated Receptor Alpha (PPARA), a protein associated with the activation of other genes and also in regulation of fatty acid oxidation during exercise. A lack of energy in the cells activate this gene like during endurance exercises or when fasting. […]

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March 17, 2017
Know Your Genes: - PPARGC1A

The PPARGC1A gene is associated with the synthesis of peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1a), which is associated with mitochondrial biogenesis or the production of new mitochondria within the muscle. Specific alleles of this gene are known to either increase or decrease the levels of PGC-1a. People with the A variant of the gene […]

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March 8, 2017
Know Your Genes: VEGFA - “The New Blood Vessel Growth Gene”

The Vascular Endothelial Growth Factor (VEGFA) gene is associated with the synthesis VEGFA, a molecule associated with the formation of new blood vessels (angiogenesis) upon training. This adaptation allows the body to increase supply of nutrients and oxygen to the trained muscles as well as remove waste products. VEGFA is associated indirectly with the widening […]

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February 27, 2017
Know Your Genes: ACTN3- “The Speed Gene”

The skeletal muscle consists of two types of fibers - fast twitch and slow twitch. The slow twitch fibers work efficiently for a long period of time while the fast twitch fibers are responsible for the short and sudden burst of power necessary for sprinting or weightlifting. The ACTN3 gene is associated with the synthesis […]

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February 23, 2017
Know your genes: COL5A1-"The Flexibility Gene"

The COL5A1 gene is associated with the synthesis of type V collagen, a key constituent of ligaments and tendons. Specific alleles of this gene are known to either increase or decrease the risk of injury. Does your 23andme, Ancestry DNA, FTDNA raw data have COL5A1 gene variant information? CHIP Version COL5A1 SNPs 23andMe (Use your […]

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November 21, 2014
Endurance Or Sprinting – What Suits You Best?

Our unique genetic profile can make some of us more suitable for endurance activities, others for more intense sprinting activities or power training. Genes involved in ‘endurance type of activities’ minimize muscle fatigue during prolonged period of mild to moderate intensity exercises, while genes involved in ‘sprinting’ relate to power, rapid bursts of energy, and […]

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