Methadone is an opioid (or narcotic) drug and a controlled substance – this drug has a risk of misuse and may cause dependence.

Acetylcholine is a parasympathomimetic drug that is used for ophthalmological applications.

The CYP2E1 enzyme makes up less than 1% of the total CYP450 enzymes and helps in clearing 2% of the total prescription drugs in the market.

CYP2D6 is responsible for the metabolism and elimination of approximately 25% of clinically used drugs.