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December 3, 2020
Hemochromatosis May Increase Risk Of Liver Cancer In Men

According to a research study by the University of Exeter Medical School in the United Kingdom, men with hemochromatosis, a common genetic disorder due to iron build-up, are ten times more likely to develop liver cancer.  What is Hemochromatosis? Hemochromatosis, also called the iron-overload disease, is a condition where too much iron builds up in […]

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June 30, 2020
APOA2 and Saturated Fats: Optimizing Your Ketogenic Diet

Our genes are a template for how our bodies work. Most people on keto diets tend to consume a high amount of saturated fats. The diet works only when the stored fat is properly broken down and used for energy. Certain variants of the APOA2 gene tend to interfere with this saturated fats metabolism and […]

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May 11, 2017
Know Your Genes: TMPRSS6 “Iron Gene”

Transmembrane Protease, Serine 6 (TMPRSS6) gene is associated with the synthesis of transmembrane protease, serine 6 (also known as matriptase-2), a liver serine protease. TMPRSS6 cleaves the bone morphogenetic protein (BMP) and down-regulates the iron hormone hepcidin, facilitating iron absorption. Inactivation of TMPRSS6 is associated with iron deficiency anemia. There are two single nucleotide polymorphisms […]

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May 4, 2017
Know Your Genes: GABPB1 “ The Energy Gene”

GA‐binding protein (GABP) transcription factor gene, also known as the Nuclear Respiratory Factor 2 (NRF2) gene is associated with the synthesis of GABPB1, a key transcriptional activator of numerous nuclear genes which produce various mitochondrial enzymes. The variants of the GABPB1 gene that code for the beta1 subunit of NRF2 protein have been shown to […]

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May 4, 2017
Know Your Genes: TTPA “Vitamin E Gene”

The Alpha-Tocopherol Transfer Protein (TTPA) gene is associated with the synthesis of alpha-tocopherol transfer protein, a fat-soluble antioxidant that is secreted by the liver, together with low-density lipoproteins into the bloodstream. Variants of this gene are associated with an increase or decrease in the level of Alpha-Tocopherol Transfer Protein, which corresponds to an increase or […]

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April 28, 2017
Know Your Genes: MC4R “Obesity Gene”

The Melanocortin 4 Receptor gene (MC4R) is associated with the synthesis of MC4R enzyme, a G protein coupled receptor which is found to bind to alpha melanocyte stimulating hormone. Among humans, this gene is shown to be associated with obesity. There are two SNPs that are used in our panel, rs17782313 and rs12970134 Association with […]

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April 25, 2017
Know Your Genes: HLADQ “The Gluten Intolerance Gene”

The Human Leukocyte Antigen system (HLA) gene is associated with the synthesis of Major Histocompatibility Complex (MHC), which are cell surface proteins that are associated with the regulation of the immune system. There are six single nucleotide polymorphisms of this gene complex, HLA DQ(rs7454108), HLA DQ 2.5 (rs2187668), HLA DQ 2.2 (rs7775228, rs2395182, rs4713586) and […]

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April 25, 2017
ACE Gene: The Key To A Fit And Healthy Lifestyle!

ACE gene: An introduction ACE gene codes for Angiotensin-Converting Enzyme. This enzyme is a part of the Renin-Angiotensin System, which is responsible for maintaining blood pressure, and fluid and salt balance in the body. The enzyme cleaves the protein angiotensin I at a particular site, converting it into angiotensin II. This angiotensin II brings about […]

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April 20, 2017
Know Your Genes: LIPC “HDL Gene”

The hepatic lipase gene (LIPC) is associated with the synthesis of hepatic lipase enzyme (LIPC) which catalyzes the hydrolysis of fat. Hepatic lipase converts intermediate-density lipoprotein (IDL) to low-density lipoprotein (LDL).It is expressed in the liver and in the adrenal glands. Specific alleles of this gene are known to either increase or decrease hepatic lipase […]

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April 19, 2017
Know Your Genes: DRD2 “Dopamine Gene”

DRD2 gene: An introduction DRD2 is a protein-coding gene that is located on chromosome 11. The Dopamine Receptor Gene (DRD2) is associated with the synthesis of DRD2, which is the main receptor for all antipsychotic drugs. The hormone Dopamine is a neurotransmitter and its secretion is increased during emotional upheavals.   From an evolutionary aspect, this […]

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