Nutrigenomics and Nutrigenetics describe the science of how genes interact with your nutrition. Though we inherently recognize by observing that two people eating the same food can have significantly different outcomes. For example, not all individuals who consume high carbs become fat, and not all obese people consume high carbs. One can find many such anomalies that seem to contradict conventional wisdom, suggesting that something more intrinsic is involved in these outcomes than just what we eat and what we do.
Here are 15 incredible nutrigenomics facts, which are sure to pique your interest and make you want to understand your genetics:
Nutrigenomics Fact 1: Nearly 70% of people have a genetic variant in the ADORA2A gene that is associated with poor sleep on increased consumption of caffeine.
Nutrigenetics Fact 2: About 65% of people carry a variant of the MTHFD1 gene that is associated with an increased risk of fatty liver on low choline intake.
Nutrigenomics Fact 3: 60% of people have a variant of the AGT gene which is shown to be associated with an increased risk for hypertension on high salt intake.
Nutrigenetics Fact 4: Nearly 15% of people have a variant of the APOA2 gene which is shown to be associated with an increased risk for obesity on high saturated fat intake.
Nutrigenomics Fact 5: Nearly 97.5% of the African American population carries a variant of the FADS1 gene, which is associated with an increased need for plant sources of PUFA. While only 50.6% of Europeans and 0% of Central Americans carry this variant.
Nutrigenetics Fact 6: Nearly 10% of people have a genetic variant in the MTHFR gene, which is associated with an increased risk of birth defects when folate levels are low.
Nutrigenomics Fact 7: About 5% of the global population carries a genetic variant in the G6PD gene that is associated with glucose-6-phosphate dehydrogenase deficiency, a condition that is mostly triggered by the consumption of fava beans.
Nutrigenetics Fact 8: About 0.2% of the global population carries a genetic variant in the HFE gene and is predisposed to Hemochromatosis when its iron intake is high.
Nutrigenomics Fact 9: About 0.2% of the global population carries a genetic variant of the SI gene, which is associated with sucrase-isomaltase deficiency when their sucrose intake is high.
Nutrigenetics Fact 10: About 0.005% of the global population carries a genetic variant in the ALDOB gene, which is associated with hereditary fructose intolerance when their fructose intake is high. About 1 in 50 adults is heterozygous for a non-functional ALDOB variant and are predisposed to hereditary fructose intolerance when their fructose intake is high.
Nutrigenomics Fact 11: About 58% of Japanese men have a genetic variant in the ALDH gene, which is associated with enhanced alcohol dehydrogenase activity and enables them to have more drinks than non-carriers.
Nutrigenetics Fact 12: About 65% of the global population carries a variant in the CYP1A2 gene, which is associated with fast metabolism of caffeine and lowered the risk for heart attack by almost 52% compared to slow metabolizers.
Nutrigenomics Fact 13: About 23% of the global population carries a variant in the AMY1 gene, which is associated with low copy numbers of the gene and reduced ability to digest starch.
70% of people from agricultural populations have an AMY1 copy number variant which is shown to be associated with better starch digestion and a lower risk of obesity when compared to 37% of non-agricultural populations
Nutrigenetics Fact 14: According to a nationwide study conducted by Metropolis Healthcare on Vitamin D, Vitamin B12, and Vitamin B9 (Folic Acid), 75% of the population has shown alarming levels of deficiency.
Nutrigenomics Fact 15: About 50% of the global population have variants in the TAS2R38 gene, which is associated with increased bitter taste perception and decreased consumption of vegetables.
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About Xcode Life's Gene Nutrition Report
Updated January 14, 2022