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One remedy for PCOS that is increasingly gaining attention is spearmint tea. Renowned for its refreshing flavor and health benefits, spearmint tea is being studied for its anti-androgenic properties, which could benefit women with PCOS. Could this common herbal tea be a game-changer in managing PCOS symptoms? This article delves into the scientific research, potential benefits, and practical considerations of incorporating spearmint tea into your daily routine.
PCOS (polycystic ovary syndrome) is a prevalent condition affecting women of reproductive age.
It usually starts in adolescence, with symptoms that can change over time.
Although PCOS is a chronic condition with no known cure, various treatments can help manage and alleviate its symptoms.
Lifestyle changes like regular exercise and a healthy diet can be helpful.
The exact cause of PCOS remains unknown, but a family history of PCOS or type 2 diabetes can increase a woman's risk, suggesting a potential genetic or metabolic link.
Spearmint tea demonstrates potential efficacy in managing PCOS symptoms, possibly due to its anti-androgenic properties.
These properties could help reduce elevated levels of androgens commonly associated with the condition.
Research indicates that spearmint has promising effects on managing PCOS symptoms. Here's what various studies have shown:
In a 2010 study, the effects of spearmint oil on PCOS were evaluated in rats.
The rats were divided into eight groups:
Rats in groups II, III, IV, and V were induced with PCOS using letrozole.
The results showed that spearmint oil reduced body weight, testosterone levels, ovarian cysts, and atretic follicles in PCOS rats.
Additionally, it increased the number of Graafian follicles, indicating a restoration of ovarian follicles.
Another recent study in 2020 assessed the impact of a combination of spearmint and flaxseed extracts on PCOS-induced rats.
24 rats were randomly divided into four groups:
Results
The treatment group witnessed:
A 2010 study in Turkey investigated the anti-androgenic properties of spearmint tea in women with PCOS and hirsutism.
42 volunteers were randomized to drink spearmint tea or a placebo twice daily for a duration of 30 days.
Study Design and Methodology
Study Results
The preliminary findings are encouraging, suggesting spearmint tea could be a helpful and natural treatment for hirsutism in PCOS.
The time it takes for spearmint tea to balance hormones can vary.
Some studies have shown that drinking spearmint tea twice daily for a month can lower testosterone levels in individuals with PCOS.
At the same time, LH and FSH levels increased compared to those who consumed a placebo.
Other research indicates that improvements can be seen as soon as five days. The effectiveness often depends on initial hormone levels.
Those with slightly elevated testosterone might see quicker results, while significantly higher levels may require additional treatments.
Hand-picked Article For You: Is PCOS An Autoimmune Disease?
Spearmint tea offers various health benefits beyond its minty flavor. Here are some key advantages:
Research shows that drinking 2-3 cups of spearmint tea daily can alleviate some symptoms of PCOS.
It is particularly effective in reducing elevated androgen levels and the severity of hirsutism (excessive hair growth).
While it holds promise for balancing hormones, individual responses may vary.
While spearmint tea is popular for its refreshing flavor and certain health advantages, excessive use can have several side effects. These include:
Others Are Reading: Top Five Teas For Better Gut Health In 2024
Here are some easy ways to enjoy spearmint tea for PCOS:
Daily consumption of spearmint tea is generally safe for most people, with minimal risks reported by experts.
However, those who are pregnant, breastfeeding, or have certain health conditions should consult their healthcare professionals. This is important to ensure spearmint tea won't adversely affect their condition.
As always, moderation is key; starting with small amounts is wise if in doubt.
Spearmint tea could potentially benefit fertility by aiding in the balance of FSH and LH levels.
In a study where women drank 2 cups daily for 5 days, there was a notable increase in LH, FSH, and estradiol.
Nevertheless, the current evidence is limited, and more research is required to fully assess spearmint tea’s effectiveness in improving fertility, especially among those with PCOS.
Spearmint tea has been consumed on an empty stomach for centuries, particularly for its potential digestive benefits.
Traditional practices often involve drinking herbal teas, including spearmint, first thing in the morning to stimulate digestive processes. Many people also enjoy the refreshing taste it leaves in the mouth.
Spearmint tea shows the potential to lower androgen levels and ease PCOS symptoms like hirsutism due to its anti-androgenic effects.
Both animal and human studies suggest spearmint tea can lower testosterone levels and improve hormonal balance, but more research is needed for definitive conclusions.
Drinking 2 cups of spearmint tea daily may be effective in managing PCOS symptoms, but individual responses can vary.
Spearmint tea also offers other health benefits, including hydration, antioxidant support, improved digestion, and potential memory enhancement.
It is generally safe for most people, but those who are pregnant, breastfeeding, or have specific health conditions should consult with a doctor before regular consumption.
Spearmint tea should be considered as part of a broader lifestyle and treatment plan for PCOS rather than a standalone solution.
https://www.who.int/news-room/fact-sheets/detail/polycystic-ovary-syndrome
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788221
https://ovarianresearch.biomedcentral.com/articles/10.1186/s13048-020-00633-8
https://pubmed.ncbi.nlm.nih.gov/19585478
https://pubmed.ncbi.nlm.nih.gov/17310494
https://www.webmd.com/diet/spearmint-tea-health-benefits
https://medlineplus.gov/druginfo/natural/845.html
https://health.clevelandclinic.org/spearmint-tea-benefits
https://onlinelibrary.wiley.com/doi/10.1002/ptr.2074
Methylation, simply put, is the addition of methyl (CH3) group to a molecule - it can be an enzyme, a hormone, or the DNA itself.
The methylation cycle encompasses a bunch of biochemical reactions that transfer methyl groups from one molecule to another - essentially like a game of passing the parcel.
Methylation is important for several functions in the body, including:
An important reaction in the methylation cycle is the conversion of an amino acid called homocysteine to another amino acid called methionine.
The buildup of homocysteine in the body has been associated with several health conditions like:
Use your ancestry test raw DNA data to get Xcode Life's Updated MTHFR and Methylation Report
$50 $30
Gene | Description |
MTHFR | The MTHFR gene produces the methylenetetrahydrofolate reductase enzyme. It converts folate into its active form. This is crucial for converting the harmful amino acid homocysteine to methionine, which is safe for the body. Two common variants in this gene are C677T and A1298C, which can lead to MTHFR enzyme activity and increased homocysteine levels. |
MTRR | The MTRR gene produces the methionine synthase reductase enzyme. It plays a role in activating another enzyme, methionine synthase (MTR). The MTR enzyme directly converts homocysteine to methionine. Variants in the MTRR gene can result in impaired reactivation of MTR, leading to a buildup of homocysteine and reduced methionine levels. |
MTR | The MTR gene produces the methionine synthase enzyme. This enzyme is responsible for the final step in the conversion of the amino acid homocysteine to methionine. Variants in the MTR gene can result in a buildup of homocysteine in the blood and decreased availability of methionine and SAM, which can disrupt DNA methylation and gene expression. |
MTHFD1 | The MTHFD1 gene produces the methylenetetrahydrofolate dehydrogenase 1 enzyme that catalyzes the 3-step folate metabolism pathway. This is an important step in generating methyl donors for the methylation cycle. Variants in this gene can alter the levels or activity of the enzyme produced, and can lead to disturbances in the methylation cycle. |
CBS | The CBS gene produces the cystathionine beta-synthase enzyme. It is crucial in the transsulfuration pathway, a branch of the methylation cycle. The CBS enzyme catalyzes the first step of converting homocysteine into another amino acid called cysteine. Variants in the CBS gene can impair this conversion, leading to increased homocysteine levels. |
AHCY | The CPS1 gene produces the carbomyl phosphate synthetase enzyme. It plays an important role in the urea cycle which converts excess ammonia in the body to urea. This cycle regulates neuronal health and oxidative stress. Variants in the CPS1 gene have been associated with higher homocysteine levels. However, the mechanism behind this is unclear. |
CPS1 | The CPS1 gene produces the carbomyl phosphate synthetase enzyme. It plays an important role in the urea cycle which converts excess ammonia in the body to urea. This cycle regulates the neuronal health and oxidative stress. Variants in the CPS1 gene have been associated with higher homocysteine levels. However, the mechanism behind this is unclear. |
BHMT | The BHMT gene produces the betaine-homocysteine S-methyltransferase enzyme. It transfers a methyl group from a compound called betaine to homocysteine to convert it into methionine. Methionine is then converted into SAMe. Variants in the BHMT gene can affect the enzyme levels or activity and may result in higher levels of homocysteine. |
NOS3 | The NOS3 gene produces the endothelial nitric oxide synthase (eNOS) enzyme. It is responsible for the production of nitric oxide in the endothelial cells. Variations in the NOS3 gene have been associated with higher homocysteine levels. The hypothesis is that nitric oxide modulates homocysteine levels through an effect on folate catabolism. |
SHMT | The MAT1A gene produces the methionine adenosyltransferase enzyme. The two forms of the enzyme, MATI and MATII, help break down methionine into S-adenosylmethionine, a main methyl donor. Variants in the MAT1A gene influence homocysteine levels. Some studies report increased levels in resposne to dietary fat intake in those who have a MAT1A variant. |
CTH | The CTH gene produces the cystathionine-gamma-lyase enzyme. It catalyzes the conversion of cystathionine to cysteine in the last step of the transsulfuration pathway. Variations in the CTH gene can lead to plasma elevation of total homocysteine levels. This can lead to a condition called cystathioninuria, an inborn error of metabolism. |
MAT1A | The MAT1A gene produces the methionine adenosyltransferase enzyme. The two forms of the enzyme, MATI and MATII, help break down methionine into S-adenosylmethionine, a main methyl donor. Variants in the MAT1A gene influences homocysteine levels. Some studies report increased levels in resposne to dietary fat intake in those who have a MAT1A variant. |
GNMT | The GNMT gene produces the glycine N-methyltransferase enzyme. It transfers a methyl group from SAM to glycine to generate S-adenosylhomocysteine (SAH) and sarcosine. Variations in the GNMT gene can result in lower levels of the enzyme, which may cause homocysteine levels to build up. However, this effect can be countered with folate intake. |
MAOA | The MAO-A gene produces the monoamine oxidase A enzyme. It is an integral enzyme in the regulation of brain chemicals like dopamine, norepinephrine, and serotonin. For MAO-A to function well, it needs to undergo optimal methylation. Undermethylation of MAO-A can result in dysregulation of brain chemicals and has been associated with panic disorder. |
COMT | The COMT gene produces the catechol-o-methyltransferase enzyme. This enzyme transfers a methyl group from SAMe (a by-product of homocysteine to methionine conversion) to brain chemicals like dopamine and norepinephrine. Variants in the COMT gene may lead to imbalances in the brain chemicals, increasing the risk of certain psychiatric disorders. |
Here, we will break down the key sections of your report and provide answers to common questions.
The MTHFR report includes:
The report focuses on the following SNPs within the MTHFR gene:
Depending on the genotype for these SNPs, your overall results are calculated. If the bar graph points to green, you likely have normal MTHFR enzyme levels.
If it’s in orange, you may need to up your dietary vitamin B9 intake.
If it’s in red, you may require a methylfolate supplement (which should be taken only after consulting your doctor).
Other than MTHFR, several important genes regulate the methylation process in the body. This section provides information on their activity.
The colored circles around the genes denote how well they function.
Red and orange indicate the presence of risk alleles that interfere with the gene functioning and are associated with lower levels or activity of the enzyme produced by that particular gene.
Green denotes a normal functioning gene and hence is associated with normal enzyme levels/activity.
“SNPs ANALYZED" provides a comprehensive overview of the specific Single Nucleotide Polymorphisms(SNPs) present in the important methylation genes, which could affect the level/activity of the enzymes produced.
Sometimes, one copy of the variant allele may be shaded in green; this is because, in some SNPs, only two copies of the variant allele will likely have a negative effect. Single copy is still considered normal.
The * symbol indicates that the original SNP we analyzed was not found in your data, so a proxy SNP was used. Proxy SNPs are variants present very close to the original SNP and, hence likely will have the same effect on the gene activity.
"I've tried other websites when it comes to getting DNA and Xcode's reports and recommendations are way on point. I got the MTHFR and Caffeine report. My smartwatch has been telling me my energy level have been at an average of 15% with stress levels of 99%. After following my reports recommendation from Xcode, my energy levels went up to 63% and my stress levels went down to 50%. Definitely going to get all of the reports as soon as possible, in order to be the healthiest version of me possible. What a find this website was."
Based on your genetic variants, the following supplements may be beneficial:
Disclaimer
Before starting any new supplement regimen, it is crucial to consult with a healthcare provider. These recommendations are based on genetic predispositions and should be tailored to your individual health needs and circumstances. Your healthcare provider can help determine the appropriate dosages and monitor for any potential interactions with medications or other supplements you may be taking.
It is good practice to review your genetic information annually or when you experience significant health changes.
Absolutely. Sharing your report with your healthcare provider can help tailor medical advice and interventions to your genetic profile. In fact, we recommend taking the help of your doctor to interpret all our reports.
Genetic testing is highly accurate, but it is one piece of your overall health picture. It is essential to consider these results alongside other medical evaluations.
Your MTHFR report is a powerful tool for understanding your genetic predispositions and taking proactive steps toward better health. Use this guide to navigate your results and make informed decisions about your lifestyle and healthcare. If you have further questions or need assistance, don't hesitate to reach out to a healthcare professional.
Did you know you could rely on bacteria to improve your health? The numerous 'friendly' bacteria in our body support our gut health efficiently. Research has focused on probiotics and prebiotics to nurture this delicate gut microbiome balance. Now, a new promising player has emerged: postbiotics, also known as metabolites or cell-free supernatants. Read on to understand what they are, where they come from, and how they can support your health in ways you wouldn't expect.
The International Scientific Association of Probiotics and Prebiotics (ISAPP) formally defined the concept of postbiotics in 2021.
According to the ISAPP, the term postbiotics refers to 'preparations of inanimate microorganisms and/or their components that confer health benefits on the host.'
Beneficial gut bacteria produce short-chain fatty acids, B vitamins, enzymes, and amino acids.
These substances are postbiotics and are important to overall health and wellness.
For instance, amino acids are the building blocks of protein, and vitamin B supports your brain health and immune function.
Thus, postbiotics are byproducts of probiotics that support your health.
Here are some examples of postbiotics:
Since probiotics are live microorganisms, keeping them alive and stable is necessary but could be a challenge.
Also, the risk of infection increases since your body is dealing with live bacteria.
Postbiotics, on the other hand, are easier to formulate and store and have a longer shelf-life.
Postbiotics are usually well-tolerated.
You won't run the risk of developing an infection or allergy.
You can take probiotics along with postbiotics for maximum health benefits.
Your gut bacteria's stability depends on age, diet, and environmental factors.
Taking them together will help maintain a balance in your gut microbiome.
Scientists have yet to fully understand how postbiotics work.
However, butyric acid, a well-known postbiotic product, might help us understand it better.
Bacteria use butyric acid, a short-chain fatty acid, as fuel.
It can alter the levels of certain bacteria in your colon.
Your colon has the highest levels of bacteria compared to anywhere else in the body.
It's important to regulate them to support your immune system.
Scientists have found that you can manipulate bacterial presence in your colon by increasing butyric acid levels.
That's an example of the effects that postbiotics have on our gut.
Some research has shown that postbiotics can improve digestive health and support the immune system.
Some additional benefits of postbiotics include:
Despite limited research, some studies have shown that postbiotics might aid weight loss.
Postbiotics like short-chain fatty acids can suppress hunger signals, thus aiding in weight loss.
You can naturally boost postbiotic levels in your body by eating probiotic and prebiotic-rich foods.
When your gut bacteria get more fiber to feed on, they naturally produce more postbiotics.
Some prebiotic-rich foods are oats, barley, chia seeds, flaxseeds, onions, and garlic.
Fermented foods like kimchi, yogurt, kefir, tempeh, miso, and sourdough bread also help boost gut bacteria.
The gut bacteria, in turn, increase postbiotics in the body.
Hand-picked Article For You: Difference Between Pre And Probiotics
Postbiotic supplements contain a concentrated dose of short-chain fatty acids, peptides, or enzymes.
They act as food for your gut bacteria and help them thrive.
They can also influence your immune system, regulate inflammatory response, and boost overall immunity.
Taking postbiotic supplements could be beneficial if you're targeting specific health concerns.
Supplements are a simple and reliable way to ensure you get your required dose.
Always consult your doctor before starting any supplements.
Most postbiotic supplements are safe.
However, you should still be careful and regularly consult your healthcare provider.
Research around postbiotic supplements is still in the initial stages.
Thus, when buying a supplement, ensure they are from a reputable brand and the health claims are backed by research.
You might be at a risk of developing an adverse reaction to a postbiotic supplement if:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9027423
https://www.nature.com/articles/s41575-021-00440-6
https://www.nature.com/articles/d42473-020-00552-8
https://pubmed.ncbi.nlm.nih.gov/32024037
https://www.healthline.com/nutrition/postbiotics
Magical black powder or just a placebo effect? Activated charcoal is a new-fangled treatment that claims to alleviate stomach bugs. Its popularity is exploding as a potential fix for various health issues. Since there's a lot of misinformation on the benefits of activated charcoal, it's essential to stay informed on its mode of action and make sense of all the data available on its efficacy. Read on to understand the usage, benefits, and risks of using activated charcoal for stomach bugs.
Stomach bugs, known as viral gastroenteritis, are intestinal infections that cause watery diarrhea, abdominal cramps, nausea, vomiting, and sometimes fever.
While generally not severe in healthy individuals, they can pose risks to infants, older adults, and those with compromised immune systems.
Now, let's talk about the causes of stomach bugs. The primary transmission routes for stomach bugs are:
Additionally, viruses can trigger stomach bugs.
Some countries, including the United States, offer vaccines to prevent viral gastroenteritis infections.
Since there's no specific cure for stomach bugs, prevention is crucial. Key preventive measures include:
Activated charcoal functions through a process known as adsorption.
It attracts and binds substances in your digestive tract, preventing them from being absorbed.
This property makes it useful in medical emergencies, such as accidental poisoning, where medical professionals use it to trap excess drugs and mitigate potential toxicity.
However, activated charcoal's role is less evident in the context of stomach bugs.
While it may bind excess fluids and potentially alleviate diarrhea symptoms by hardening stools, it does not address the underlying cause.
Activated charcoal cannot eliminate the viruses, bacteria, or parasites that typically cause stomach bugs.
Activated charcoal is not a treatment or preventative strategy for stomach bugs.
Activated charcoal can adsorb toxins, but viruses, bacteria, or parasites cause the disease.
While some limited evidence shows that charcoal may help with diarrhea, a frequent symptom of stomach infections, its overall effectiveness remains to be determined.
Some studies suggest using it to control diarrhea in palliative care, but its benefits need further research.
Most stomach bugs disappear on their own within a few days.
Relaxation and enough water intake are the most effective strategies for acquiring fluids and electrolytes lost due to vomiting or diarrhea.
Doctors don't recommend activated charcoal to treat a stomach virus.
This condition does not respond to activated charcoal because it lacks antiviral, antibacterial, or antiparasitic properties.
Scientific evidence supporting its effectiveness against the stomach virus is limited.
Therefore, it's generally advised not to use activated charcoal for stomach viruses.
Activated charcoal can help with gut bacteria, particularly in cases of diarrhea resulting from bacterial infections.
A 2017 study highlights activated charcoal's ability to attract and expel ingested toxins from the gastrointestinal tract, like harmful bacteria whose toxins cause diarrhea.
Activated charcoal adsorbs these substances on its surface and prevents them from being absorbed into the body, thus helping to manage diarrhea symptoms.
However, while it shows promise, more research is required to fully understand its effectiveness and potential benefits in managing gut bacteria-related conditions.
Age Group | Dosage (grams) |
Children <1 year | 10g to 25g |
Children 1 - 12 years | 25g to 50g |
Teenagers and Adults | 25g to 100g |
Yes, there are risks with taking activated charcoal for stomach bugs.
Inhaling charcoal can cause side effects like vomiting, bowel blockages, and aspiration pneumonitis.
Aspiration pneumonitis is a severe lung problem that can make breathing hard.
People at higher risk for these side effects include those who:
Giving activated charcoal to an unconscious person is also risky.
It can cause vomiting, which could lead to choking.
If someone with vomiting and diarrhea becomes unconscious, it is a medical emergency.
So, while activated charcoal can help with stomach bugs, it's essential to talk to a doctor first to avoid these risks.
Activated charcoal is not suitable for everyone.
Doctors advise against using activated charcoal for patients with an unprotected airway, particularly those who are barely conscious.
It could cause severe breathing problems or even death from accidental inhalation (aspiration).
Here are the conditions under which you should avoid activated charcoal:
It's best to have your doctor monitor you in these conditions.
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Activated charcoal can be helpful in certain situations, but using it safely and correctly is crucial.
Here are some precautions to keep in mind when using activated charcoal:
Call poison control or a healthcare professional immediately if poisoning occurs.
For treating poisoning, the recommended dosage is:
For multiple doses, after the initial dose, the recommended amounts are:
Always seek professional advice before using activated charcoal.
https://www.mayoclinic.org/diseases-conditions/viral-gastroenteritis/symptoms-causes/syc-20378847
https://www.webmd.com/vitamins-and-supplements/activated-charcoal-uses-risks
https://www.medicalnewstoday.com/articles/activated-charcoal-for-a-stomach-bug
https://pubmed.ncbi.nlm.nih.gov/29231746
https://www.niddk.nih.gov/health-information/digestive-diseases/viral-gastroenteritis/treatment
https://www.healthline.com/health/activated-charcoal-gastroenteritis
https://www.tandfonline.com/doi/full/10.1080/03007995.2017.1416345
https://www.mayoclinic.org/drugs-supplements/charcoal-activated-oral-route/proper-use/drg-20070087
Have you taken an ancestry test with 23andMe, AncestryDNA, or other companies? Then, you're already on the path to unlocking the incredible insights within your raw DNA data. This article delves into the world of DNA raw data analysis, guiding you through the tools to help decode the secrets hidden within your genes. Are you ready to discover the best platform to upload raw DNA data? Join us as we explore the top 10 tools that can help you get the best out of your raw DNA!
Your DNA is a complex instruction manual written using only four letters: A, T, G, and C.
Each human has a unique manual of their own.
These manuals are 99.99% similar across humans, but the 0.01% can make a big difference.
For instance, some people could have an A in a spot where a C should be instead.
A raw data file from companies like 23andMe or AncestryDNA digitally tabulates these differences, which are called single-nucleotide polymorphisms (SNPs).
Here’s a small example of what data might look like in a raw DNA file:
SNP | Chromosome | Position | Genotype |
rs123456 | 1 | 12345678 | AT |
rs789101 | 2 | 910112132 | GT |
rs445566 | 3 | 98765432 | CG |
Raw data contains a list of variant loci on your DNA called SNPs. Scientists and researchers can use this raw data to study and learn more about genetics, human ancestry, and even some health conditions.
They can compare your genetic markers with those of others to find patterns and make connections.
SNPs are little tweaks to your DNA that make you unique. While 99.99% of your DNA is the same as everyone else’s, it’s that 0.01% that makes all the difference.
SNPs can also tell you about your ancestral roots. They help trace where your ancestors came from and how they migrated for thousands of years. That’s how companies like 23andMe can tell you you’re 30% Irish or 10% Native American.
Certain SNPs have links to health conditions. For instance, a specific SNP could increase your risk for conditions like heart disease, diabetes, or certain cancers. An awareness of your risk for health conditions can help you take the necessary preventive measures or get screened early.
Your SNPs can offer insights into how your body responds to different exercise plans or diets. You can optimize your workout routine and nutrition plan based on what works best for your genetic profile.
It’s important to remember that raw DNA data is a blueprint of your genetic information.
It can reveal sensitive personal details, and you should handle it carefully.
Only share it with trusted sites that maintain your privacy and data security.
We’re here to help you with just that!
The DNA data file from genealogical tests has information on around 700,000 SNPs in your DNA.
The portions of DNA close to each other (markers) are often passed down together.
Genetic ancestry tests use these markers to track your lineage and report ancestry and ethnicity.
They compare your DNA data with that of millions of other people and find regions of similarity.
The more the similarity, the more closely you are related to that person.
However, this information is only a drop of water compared to the ocean of information you can get from your DNA raw data file.
There are many third-party tools and DNA upload sites that interpret your DNA raw data for you.
Some of the well-known DNA raw data analysis tools are Xcode Life, Genome, Stratagene, and GEDMatch.
Note: Most of these companies accept only genotyping raw data (like the ones from 23andMe and AncestryDNA).
Analyzing your DNA raw data can tell you much about your health and wellness.
You can get insights into your:
Learning so much about yourself has never been this simple.
Many third-party companies allow you to upload your DNA raw data to provide easy-to-understand genetic reports on health and wellness.
Tool | Price | Categories covered |
Xcode Life - the highest number of reports - 3000+ markers analyzed - 750 + traits covered | Starting at $30 (Free reports available with pack products) | Nutrition Fitness Allergy Skin Health Sleep Personality BRCA and Breast Cancer MTHFR and Methylation Personalized Medicine Caffeine (free) |
Promethease | $12 | Basic health and reports |
Genetic Genie | Free; Option for voluntary donation starting from $5. | Only methylation and detox analysis |
GEDMatch | 3 free tools, 45+ premium tools. | Ancestry. Mainly for family matches using combined 23andMe, Ancestry DNA, Family Tree DNA databases. |
Genomelink | Free (~100 traits); $14 monthly subscription for 312 traits | Nutrition, personality, intelligence, physical, and sports traits |
SelfDecode | 1 free report; $278-$695 and $99 annual memebership fee | Nutrition, fitness, and health |
MyTrue Ancestry | Basic version is free.; Membership costs up to $596 | Ancestry reports only |
Genomapp | 3 reports are free; Other reports cost up to $25 | Health conditions and precision medicine |
Livewello | 1 free trait; Up to $25/month subscription | Nutrition and Precision Medicine |
Strategene | $95, only one report | Metabolic pathway information |
Enlis Genomics | 1 free report; Other reports up to $80 | Scientific health reports only |
Nutrahacker | 1 free report, other reports up to $145 | Genetic traits, nutrition, metabolism, fitness, lactation etc |
DNAFit/Circle DNA | 5 bundle reports ($379) | Fitness, medicine, skin, mental health, maternal health etc |
Happy choosing!
Xcode Life is a global genetics and bioinformatics company that analyzes raw DNA data files from companies like 23andMe, AncestryDNA, FTDNA, MyHeritage, and LivingDNA.
Xcode provides a variety of expertly curated reports, starting at just $20.
The reports contain specific, helpful recommendations for people with the same genetic type.
They are delivered within 24 hours.
Report interpretation assistance is also available upon request.
Xcode provides bundle options, consolidating over 1000 traits into a single analysis report.
Professional practitioners such as physicians, surgeons, nutritionists, sports trainers, chiropractors, and more use Xcode for their raw DNA data analysis needs.
Get your 23andMe raw data analyzed here.
Promethease is a software program that was developed by SNPedia to perform raw data analysis.
It uses your 23andMe raw data to generate disease-based reports.
They charge $12 per report.
It’s important to note that Promethease reports may be overly technical for most users, who usually don’t have expert knowledge of polymorphisms and biostatistics.
The system is based on literature search and retrieval.
It builds a report based on the SNPedia database against the raw DNA data from sites like AncestryDNA, 23AndMe, or FamilyTreeDNA.
The reports primarily contain information about health and precision medicine.
For instance, the report can mention your genetic risk for diseases like Alzheimer’s.
Though it is a popular service, its scientific integrity is often questioned due to its reliance on SNPedia, an open-source service.
Promethease was originally offered free of charge. However, MyHeritage acquired the DNA analysis service in 2019.
They maintain SNPedia as a free resource for academic and non-profit users.
Non-European users’ DNA raw data was shifted into new accounts on MyHeritage.
Users retain ownership of their DNA raw data file and may delete their data from MyHeritage’s server at their discretion.
Genetic Genie provides free methylation and detox reports.
This tool uses your DNA raw data from companies like 23andMe and AncestryDNA to perform methylation analysis.
The site also provides a tool for a detox analysis that looks for defects in the cytochrome P450 detox enzymes.
Incorrect methylation leads to a wide range of serious medical conditions.
This makes the methylation profile offered by Genetic Genie a good report.
The following genes are included in Genetic Genie’s Methylation panel:
14 markers in these genes are reported in the panel.
The detox profile looks at single nucleotide polymorphisms (SNPs) in genes that affect the detoxification pathway of the body.
The following genes are included in Genetic Genie’s Detox panel:
22 markers in these genes are reported in the panel.
This is a free service, but a voluntary donation starting from $5 is accepted.
MTHFR Report: Xcode Life vs. Genetic Genie - In-depth Analysis
GEDMatch is a platform that helps understand your lineage via raw DNA files from genealogy companies.
The service is free, but the user experience can seem challenging for users who need to be used to exploring genetic data to understand the reports.
GEDmatch provides a range of complimentary tools and a selection of more advanced features that require a paid subscription.
You can log in to your GEDmatch account in 4 simple steps:
If you forgot your password, you can reset it with this link
Once you create your account, you can upload your raw DNA data here.
On the upload page, you’ll need to enter the following details:
Once the upload is successful, you should be assigned a kit number.
GEDmatch provides three free tools:
Purchasing a Tier 1 membership at $10 per month unlocks access to:
Various online genealogy groups recommend the GEDmatch tool.
Interestingly, GEDmatch helped law enforcement to arrest the Golden State Killer, responsible for more than 50 rapes and at least 13 murders in the 1970s and 80s.
Ever since then, GEDmatch has gained popularity as a crime-solving tool.
Read an in-depth review of GEDMatch here.
Genomelink lets users upload raw DNA data from 23andMe, Ancestry, or MyHeritage.
The site can also connect directly to their accounts on these websites to retrieve their DNA data.
Users who upload DNA data will receive a free report on 100 traits immediately.
However, to unlock more traits, you’ll need a subscription to their website for $14/month, which may not be cost-effective.
If you sign up, all your reports will be consolidated and presented in your dashboard, which you can only access online.
It’s important to note that downloadable PDF reports are unavailable from Genomelink.
A feedback option near each trait can help you review how accurate the trait results are.
Overall, they provide over 352 traits across 20 reports.
Most of these reports are genealogical and focused on revealing ancestry.
Their website does not advertise bundled reports anymore.
The actual prices of each report remain concealed until a user creates an account with Genomelink.
Follow these steps to log in to your Genomelink account:
Genomelink can be a good, cost-free place to start if you are new to genetic tests.
The results are moderately user-friendly and readable.
They seem to have in-depth information on privacy and the use of users’ data.
The free version of Genomelink is worth a try.
However, think twice before purchasing a subscription.
The primary benefit of the subscription is that Genomelink emails you one trait result each week.
The report bundles are overpriced for the number of traits they cover.
Although the sample reports look visually appealing, the web-based reports could tell a different story.
Genomelink Traits and Reports – A Comprehensive Review [2025]
SelfDecode offers personalized DNA testing and provides health and wellness reports by analyzing your genetic data.
It also offers genome analysis with a personalized genetics blog that helps you understand your DNA results.
Once you create a SelfDecode account, you can upload your raw DNA data.
A free report for a few traits is generated within a couple of hours.
The annual membership subscription fee for SelfDecode is $99.
Depending on the services you’re interested in and whether or not you already have a raw DNA file, the total upfront payment can range from $298 to $695.
After that, you will be billed a $99 fee annually.
SelfDecode Review: What You Should Know Before Buying
Livewello accepts raw data files from 23andMe, AncestryDNA, Family Tree DNA, and Gene By Gene.
It offers 15 genetic reports and 160 health reports. However, the range of these reports is much smaller, with only a few SNPs studied per report.
Some of the reports include:
You can create an account for free, but reports require a membership.
Livewello’s payment plans range from $6.95 to $25 monthly or $75 to $215 yearly, with progressively better amenities.
A DNA kit may be purchased for $165 if required.
Livewello offers 20 reports. Some of them include:
StrateGene initially offered a $295 DNA kit as the only sample collection model.
Now, they have switched to a virtual DNA data upload model.
You can upload your DNA raw data files from 23andMe to StrateGene.
They offer one report, priced at $95, with information on nine essential processes in your body, including pathways for:
Users find the reports too complex to be of actual use.
Strategene may not be the best choice for those who prefer easily understandable results and readily implementable recommendations.
This 23andMe raw data analysis service provider is more for educational than direct consumer purposes.
Their service caters to research scientists.
They analyze DNA data to find health risks associated with specific genetic variants.
The initial intention of developing this software is to allow researchers to analyze whole genome files.
They have also added a software program for personal use and a free genome report accessible directly from their site.
While the service is free, understanding and interpreting the report takes a reasonable amount of scientific knowledge.
Nutrahacker accepts raw DNA data from 23andMe, AncestryDNA, tellmeGen, or MyHeritage.
Upon registering with your details and uploading your raw DNA data, you can access a ‘Genotype Imputation’ report for free.
NutraHacker offers eight other genetic reports, including:
They advertise two bundle packs, a Detox and PharmaShield panel($300/year) and the WGS Critical Genetics panel ($395 one-time).
DNAFit now redirects to CircleDNA. They offer five categories of analyses, including:
Each of these reports costs $379 and includes collection kits.
A children’s DNA kit is available for $299 as well.
The report is available online.
Initially, the information feels overwhelming.
However, the reports do have reasonably relevant background information.
The reports comprehensively include a list of the genes analyzed in the test and information about each gene.
If you are a hardcore athlete, consider CircleDNA.
Before you buy, check out our comparative blog on the top 5 DNA fitness report providers.
According to DNA Testing Choice, a popular genetic testing company review website, their privacy policy contains clauses regarding how DNAFit could pass on user data to third parties for research with or without client consent.
Lifenome accepts DNA raw data files from 23andMe, AncestryDNA, and FamilyTreeDNA.
They offer reports on the following traits:
The reports are comprehensive and easy to understand, with clear implications and recommendations.
The site does not clearly indicate pricing or how to purchase these reports, which could deter some users from using Lifenome’s services.
With the most reports and over 750 traits analyzed rapidly, Xcode Life is undoubtedly the best raw DNA data analysis tool in 2024.
Additionally, its website is user-friendly and compatible with 10+ DNA testing companies, including 23andMe, AncestryDNA, and FTDNA.
Xcode provides comprehensive, jargon-free, and interactive reports starting at just $20 with clear recommendations and information on each trait marker analyzed.
GenomeLink has a user-friendly website with different products that users can apply to all walks of life.
They provide a free report with over 100 traits upon account creation.
While the reports appear lucrative, it’s important to note that the rest of their reports and traits are accessible only through a $14/month subscription. Additionally, the value of their report bundles does not match their cost.
Despite this, their reports can help users understand their ancestry, curate their diets, and improve their workouts for a healthier lifestyle.
SelfDecode offers whole genome analysis, generating readable reports within a few hours.
It also offers free trait reports for a handful of markers upon account creation.
The comprehensive nature of these reports can significantly improve consumers’ knowledge of their disease risk and behavioral patterns.
Users thus remain informed and prepared on their genetic makeup.
Several genetic testing companies offer services to analyze raw DNA data and provide helpful insights about health and wellness.
Xcode Life stands out due to its affordable, comprehensive, and user-friendly genetic reports that are delivered within 24 hours.
Your raw data likely contains the following columns: RSID, chromosome, position, and genotype.
Each row analyzes the genotype of an SNP (single nucleotide polymorphism), or a mutation in your DNA, at a certain position on a specific chromosome.
Genetic testing companies like Xcode Life can decode your raw data to give you valuable information about your health and wellness for as little as $30.
While some companies may offer a couple of health-related reports for free, getting a comprehensive health report from your raw DNA can give you a clear picture of your overall wellness and possible risks.
Xcode Life offers a comprehensive Gene Health report that studies your risk for over 45 chronic conditions for just $50.
While most genetic testing companies charge over $100 for their DNA analysis services, Xcode Life offers individual reports priced between $30 and $50, with comprehensive report bundles priced between $160 and $199.
Inflammation is a complex process that, in many cases, is essential for our body's defense and healing. However, when it becomes chronic, it can lead to a host of health issues. Managing chronic inflammation requires a holistic approach, including a balanced diet, regular physical activity, and effective stress management. This guide focuses on the first pillar: nutrition. Discover how an anti-inflammatory diet can help you control inflammation and improve your overall health. We'll provide you with a comprehensive food list and meal ideas in a downloadable PDF, making it easier for you to incorporate these anti-inflammatory foods into your daily routine. Let’s dive into the ultimate guide to an anti-inflammatory diet and learn which foods to embrace and which to avoid.
Inflammation is not an enemy in typical cases. When your immune system identifies something as foreign, it triggers an inflammatory response, protecting your body against viruses and other pathogens.
However, in some cases, the inflammation continues to persist even if there's no foreign invader.
This is where inflammation is the enemy, as it can increase your risk for conditions like:
An anti-inflammatory diet focuses on consuming foods that help naturally reduce inflammation in the body while avoiding foods that can trigger or worsen inflammation.
If you have a health condition that causes chronic inflammation, consuming an anti-inflammatory diet may alleviate your symptoms.
While the anti-inflammatory diet is safe, you must consult your doctor before starting it.
An anti-inflammatory diet benefits people with conditions that are caused by or worsen due to chronic inflammation. Some of these include:
Some research also states that eating an anti-inflammatory diet may reduce the risk of cancer.
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There are different types of anti-inflammatory diets, depending on the foods they recommend. Let’s take a brief look at the three most popular ones!
This diet focuses on the consumption of:
It recommends avoiding the following foods:
DASH, or the Dietary Approaches to Stop Hypertension, is similar to the Mediterranean diet, which focuses on consuming less or no salt and includes more low-fat dairy products.
This diet combines a few parts of the Mediterranean diet with the DASH diet and is considered healthy for the brain.
It may guard against Alzheimer’s disease and other forms of dementia.
The MIND diet recommends the consumption of:
Like other anti-inflammatory diets, the MIND Diet advises limiting the following foods:
Foods to Increase | Foods to Decrease |
Fruits and Vegetables - Berries, cherries, peppers - Sweet potato, pineapple, yellow bell pepper, squash, peaches - Dark leafy greens, Brussels sprouts, cabbage, green beans - Blueberries, blackberries, grapes, eggplant, olives, plums, purple cabbage | Proteins - Grain-fed beef - Processed meats |
Fiber - Whole grains - Bran cereal - Nuts - Brown rice - Potato | Trans-fats - Partially hydrogenated oils - Baked goods - Fried foods |
Proteins - Plant-based proteins (found in beans, legumes, nuts and seeds) - Grass-fed meat and fish | Saturated fats - Meats like lamb, pork, fatty beef, chicken with skin - Dairy products - Fruit juices |
Herbs & Spices - Ginger - Turmeric - Sage - Cumin - Cloves - Cinnamon - Paprika - Tarragon | |
Omega-3’s - Fatty fish - Fish oil - Whole grains - Walnuts *Eat more omega-3 fatty acids than omega-6 fatty acids. | |
Monounsaturated Fatty Acids - Olive oil - Avocados | |
Desserts/Snacks Dark chocolate containing 70% or more cocoa |
Oily or fatty fish, like sardines, salmon, trout, and herring, are rich in omega-3 fatty acids.
These fatty acids have been associated with a reduction in C-reactive protein, a key inflammation marker.
Several beverages and drinks can help reduce inflammation. Some of these include:
Omega-3 fatty acids are the most potent natural anti-inflammatory.
They are found abundantly in the following foods:
Others are reading: MTHFR Diet: What To Eat, What To Avoid For MTHFR Mutation
An anti-inflammatory diet may take a few weeks to become effective.
We must remember that an anti-inflammatory diet is not a magic pill; it can take longer than six or seven weeks to show effects.
If you are on an anti-inflammatory diet, you must limit or avoid the consumption of the following foods: